Who are the Biggest Favorites, Underdogs for Week 3 in College Football?

Iowa State are massive favorites in Week 3 against UNLV.
Iowa State are massive favorites in Week 3 against UNLV. / Steven Branscombe-USA TODAY Sports
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College Football has seen some big upsets already in 2021. Texas got pummeled by Arkansas, Ohio State and Georgia have already gone down, and the FCS Montana Grizzlies took out the Washington Huskies. A lot has happened!

If you’re looking for best bets, upset picks, or wondering which lines could be a trap, they’re all available on our College Football homepage.

Before the Saturday kickoff, here is a look at the biggest favorites and underdogs for the Week 3 slate, with all odds via WynnBET.

Biggest Favorites and Underdogs in College Football Week 3 Odds

New Mexico vs. No. 7 Texas A&M

Spread: Texas A&M -29.5

After the injury to starting quarterback Haynes King, Jimbo Fisher has put Zach Calzada under center, with mixed results.

Connecticut vs. Army

Spread: Army -34.5

Connecticut has the 179th-ranked rushing defense, allowing 189.7 rushing yards per game. Army has the eighth-ranked rushing offense, averaging 298.5 rushing yards per game.

Northern Illinois vs. No. 25 Michigan

Spread: Michigan -27.5

Michigan’s offense is averaging 339 rushing yards per game, fifth-best in college football, and their defense is averaging just 12 points against.

Georgia Tech vs. No. 6 Clemson

Spread: Clemson -28.0

Clemson does not rank in the Top-100 in passing yards, rushing yards, or points per game, but their defense has allowed just 13 points in the first two games.

Old Dominion vs. Liberty

Spread: Liberty -27.0

Liberty quarterback Malik Willis leads his 2-0 team in both passing and rushing yards. 

South Carolina vs. No. 2 Georgia

Spread: Georgia -31.5

Both teams enter Week 3 with top ten defenses in terms of passing yards against and points allowed.

No. 14 Iowa State vs. UNLV

Spread: Iowa State -32.5

Iowa State has failed to cover the spread in their first two games, and find themselves with a lofty spread on the road against UNLV.


Which favorites or underdogs will cover the spread in Week 3? Make your pick at WynnBET.