MLB Picks

Best MLB Parlay Picks Today (Four Favorites Plus a Holiday Bonus Special)

Joe Summers
Alek Manoah finds himself as a short favorite and headlines several games with value
Alek Manoah finds himself as a short favorite and headlines several games with value / Cole Burston/GettyImages

It's time for my favorite piece of the day! We've got a long weekend ahead, why not cruise into the holiday with some extra wads of cash?

There's 14 MLB games on tap for today and as always, the BetSided team has you covered from every angle. Matt de Saro narrowly missed a big parlay hit yesterday, so I'll do my best to keep the good vibes rolling.

May Showers bring May Dollars, or something like that. Using the odds from WynnBET Sportsbook, here are my favorite MLB parlay picks on this glorious Friday:

Best MLB Parlay Picks Today

The Friday Favorites Parlay (+556)

Astros (-200) vs Mariners

The Astros are my favorite play on the board today but we'll play it safe with the moneyline for the sake of the parlay. Justin Verlander hasn't allowed a single run in his last three starts and has a 0.55 ERA in five road outings. The dude is the best pitcher in the American League, and he's won his last five outings by a combined score of 25-5.

Houston has won eight of 10 as a road favorite and should tee off on Chris Flexen, who ranks in the bottom-10 percent in every major pitching metric. Flexen has 6.98 ERA in May and Seattle has lost five consecutive games he's started. Astros roll.

Blue Jays (-115) vs Angels

Any time you get Alek Manoah at short odds like -115, you have to take it. He's yet to allow more than two runs in a single outing and has a quality start in all but one of his eight appearances. The Blue Jays are 6-3 over their last nine as their offense is heating up, and dating back to last season Toronto has won 16 of Manoah's 20 starts.

Chase Silseth is making just his third career start and first against someone other than Oakland. He gave up two home runs to the A's in his last outing and between Vlad Guerrero Jr., Bo Bichette, Lourdes Gurriel Jr., and George Springer, there's a ton of power in Toronto's lineup.

Give me the Blue Jays to push Los Angeles to 3-7 over their last 10.

Giants (-210) vs Reds

The Reds exploded their most runs since 1999 against Chicago yesterday, scoring 20 in an absolute beat-down. But I'm fading them today against Carlos Rodon and the Giants. If you remove Rodon's disaster outing against St. Louis, he hasn't allowed more than two runs in a single game while compiling a 1.98 ERA in the process.

Cincinnati is expected to start Graham Ashcraft, who gave up two runs in four innings against Toronto in his first big league start last week. The Giants rank seventh in OPS against right-handed pitchers this month and should find success against Ashcraft and the National League's worst bullpen behind him.

San Francisco is 9-3 in their last dozen games as a road favorite and should bring the Reds back down to earth.

Red Sox (-170) vs Orioles

After taking two of three from the White Sox, Boston has now won seven of eight behind the league's most powerful lineup. The Red Sox lap the field in OPS during May and are averaging a ridiculous 7.69 runs per game in the last two weeks.

Kyle Bradish ranks in the third percentile in average exit velocity and has a 6.53 ERA this month. He won't contain Boston, but Garrett Whitlock should be able to contain the Orioles. Whitlock is in the 83rd percentile in strikeout rate and Baltimore averages more strikeouts per game than all but three other teams.

The Orioles are 6-16 on the road this season, including 1-5 in their last six. Back the Red Sox to take advantage and win their fourth straight at home.

Holiday Bonus Special (+4830)

If you're feeling adventurous, I've got a trio of unders to add to the Friday Favorites to create a true whammy of a parlay heading into Memorial Day weekend.

Pirates vs Pirates Under 7.0 (-105)

The under is 7-2 in San Diego's last nine and they take on one of the premier under teams in the league today. Pittsburgh's offense is dreadful and they should struggle against Sean Manaea, who has a quality start in six of his eight outings this year. In the Pirates' last 13 as a road underdog, the under is 9-4.

But San Diego should struggle against Jose Quintana as well, as Quintana sports a 1.66 ERA this month and has only surrendered more than two runs once in eight starts. The under is 14-6 in the Padres' home games this year, including hitting in three straight. Expect those trends to continue today.

Guardians vs Tigers Under 7.0 (+110)

Detroit is 29-13-2 to the under this season thanks to an excellent pitching staff and pathetic lineup. It's 14-3-3 in their last 20 games and has hit in each of Alex Faedo's last three starts. He's yet to allow more than three runs in an outing and faces a Guardians lineup today that ranks 28th in OPS against right-handed pitchers this month.

That's one spot worse than the Tigers, by the way, who have a difficult matchup with Shane Bieber. In five road starts, Bieber has a 2.45 ERA and just held the Tigers to two runs over seven innings while striking out 10. The under is 5-1-1 in Cleveland's last seven and has hit in three straight when they're a favorite. As a cherry on top, it's 4-1 in Bieber's previous five outings.

Yankees vs Rays Under 7.5 (-120)

These are two powerful lineups, but the Yankees are much worse against left-handed pitchers than righties. Rays' starter Jeffrey Springs has burst onto the scene and is a southpaw New York should struggle mightily against. He's only allowed five hits in 10.1 scoreless innings over his last two starts, and his MLB Statcast pitching profile is a sight to behold:

from Baseball Savant
from Baseball Savant /

Meanwhile, Jameson Tallion has a 2.70 ERA in May and is coming off seven strong innings against the White Sox in which he allowed only one run. Most bettors would see this low total and slam the over, given the prowess of these lineups. But with two stellar starting pitchers and excellent bullpens behind them, the under is the play.


The Friday Favorites Parlay (+556)

  • Astros (-200) vs Mariners
  • Blue Jays (-115) vs Angels
  • Giants (-210) vs Reds
  • Red Sox (-170) vs Orioles

Holiday Bonus Special (+4830)

The Friday Favorites PLUS:

  • Padres vs Pirates Under 7.0 (-105)
  • Guardians vs Tigers Under 7.0 (+110)
  • Yankees vs Rays Under 7.5 (-120)

WHEW! What an action-packed day ahead. With so much value on the board, feel free to mix-and-match to create your perfect parlay, but be sure to head to WynnBET to get it locked in before odds can change.

I'll be playing both parlays and can't wait to break in the new grill I'll buy with all of my winnings. May Showers bring May Dollars, after all. Let's get after it.

Follow all of Joe Summers' betting picks here.