Bills vs. Dolphins: Odds, Spread, Over/Under and Prediction for NFL Week 2

The Miami Dolphins host the Buffalo Bills in Week 2.
The Miami Dolphins host the Buffalo Bills in Week 2. / JAMIE GERMANO/ROCHESTER DEMOCRAT AND

Bills Mafia exited Highmark Stadium in Orchard Park dejected on Sunday after a 23-16 loss to the Pittsburgh Steelers.

The Buffalo Bills went into halftime up 10-0, only to let Pittsburgh pick them apart in the second half. Buffalo allowed just 251 yards of total offense to the Steelers, but was charged with a devastating eight penalties that continuously gave away chunks of field position. 

The Miami Dolphins started their season right, getting a win over their divisional foe, the New England Patriots.

Dolphins quarterback Tua Tagovailoa picked up two touchdowns, one in the air and one on the ground. The Miami defense may have played the biggest role, causing four fumbles, including a crucial forced fumble late by defensive back Xavien Howard that got the Dolphins the football back, helping Miami to churn down the clock.

Here’s how the odds at WynnBET Sportsbook look for this Week 2 matchup:

Bills vs. Dolphins Spread, Odds, and Over/Under


Buffalo -3.5 (-105)

Miami +3.5 (-115)


Buffalo: -170

Miami: +145


48.5 (Over -110/Under -110)

Bills vs. Dolphins Betting Trends:

  • The over is 5-0 in the last five meetings between the Bills and Dolphins.
  • The Dolphins are 4-0 against the spread in their last four games as an underdog.
  • The Bills are 3-2 against the spread in their last five games as a favorite.
  • The last meeting between Buffalo and Miami had a total of 82.

Bills vs. Dolphins Prediction and Pick

The Bills are a trendy Super Bowl pick right now, and they’re looking to bounce back after the loss to Pittsburgh, but I don’t think it will come easy.

Miami’s defense looked extremely pesky this week, and I think they will give Josh Allen and Buffalo’s suspect running game a hard time.

I’ll take the Dolphins at home to cover the spread. Tagovailoa is a game manager that makes very few mistakes, and I think that is the No. 1 thing needed in beating this Buffalo team. Ben Roethlisberger just proved it last week, and Tua will look to reenact it this week.

Will the Bills or Dolphins cover the spread? Make your pick at WynnBET.