NFL Week 16: Picks, predictions and more

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JACKSONVILLE, FL – DECEMBER 17: The Jacksonville Jaguars take the field before the start of their game against the Houston Texans at EverBank Field on December 17, 2017 in Jacksonville, Florida. (Photo by Sam Greenwood/Getty Images) /

Jacksonville Jaguars (-4.5) at San Francisco 49ers

The 49ers (4-10) are playing really good football with Jimmy Garoppolo under center, but the Jaguars (10-4) will find a way. Jacksonville has an incredible defense, so if Blake Bortles can just hold onto the football, it should be an AFC South title.

Pick: Jacksonville 19, San Francisco 17

New York Giants at Arizona Cardinals (-3.5)

Drew Stanton. Steve Spagnuolo. Nothing on the line. It’s the Cardinals (6-8) and Giants (2-12)!

Pick: Arizona 24, New York 20

Seattle Seahawks at Dallas Cowboys (-4.5)

Dallas (8-6) is still faintly alive in the NFC playoff picture, while Seattle (8-6) can technically say the same. The Cowboys get Ezekiel Elliott back in the fold, which should be enough to push them over the top.

Pick: Dallas 29, Seattle 24

Pittsburgh Steelers (-8.5) at Houston Texans

It’s T.J. Yates and Bill O’Brien getting plastered by Pittsburgh (11-3)! Merry Christmas!

Pick: Pittsburgh 26, Houston 12

Oakland Raiders at Philadelphia Eagles (-9)

Philadelphia (12-2) is trying to get home-field advantage in the NFC, and the listless Raiders (6-8) aren’t getting in the way.

Pick: Philadelphia 28, Oakland 13

Last Week: 12-4
Season: 141-83