NFL Week 12 2020: Picks and predictions for each game

Tom Brady, New England Patriots, Patrick Mahomes, Kansas City Chiefs. (Photo by Maddie Meyer/Getty Images)
Tom Brady, New England Patriots, Patrick Mahomes, Kansas City Chiefs. (Photo by Maddie Meyer/Getty Images) /
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CLEVELAND, OHIO – NOVEMBER 22: Sione Takitaki #44 of the Cleveland Browns celebrates a touchdown during the first half against the Philadelphia Eagles at FirstEnergy Stadium on November 22, 2020 in Cleveland, Ohio. (Photo by Jason Miller/Getty Images)
CLEVELAND, OHIO – NOVEMBER 22: Sione Takitaki #44 of the Cleveland Browns celebrates a touchdown during the first half against the Philadelphia Eagles at FirstEnergy Stadium on November 22, 2020 in Cleveland, Ohio. (Photo by Jason Miller/Getty Images) /

53. 1-9. 52. 7-3. CBS. Sunday, Nov. 29. CLE -6.5. 1 p.m. ET

The Browns are moving towards their first postseason berth since 2002, while the Jaguars have lost nine straight. Yes, Baker Mayfield is potentially a pitfall here, but smart money says Cleveland runs the ball 45 times.

Pick: Cleveland 28, Jacksonville 20

13. Sunday, Nov. 29. 7-3. 16. CBS. BUF -5.5. 1 p.m. ET. 3-7

A sneaky-fun game. The Bills are really good, coming off their bye and trying to win the AFC East for the first time since 1995. However, Justin Herbert is fantastic, his weapons are solid and Buffalo’s defense isn’t good. This should be a shootout in the cold.

Pick: Buffalo 34, Los Angeles 31

CBS. 44. 1 p.m. ET. 6-4. 28. Sunday, Nov. 29. 3-7. LV -3

This screams, screams let-down game for the Raiders. After losing a tough game at the wire against Kansas City, does Las Vegas take care of business against the Falcons, or go into a cross-country coma and lose in the sterile environment of Atlanta?

Pick: Atlanta 30, Las Vegas 28

CBS. 0-10. 30. 1 p.m. ET. 6-4. 59. Sunday, Nov. 29. MIA -7

Look, it’s the Jets. Win a game. Until then, picking against them every week is the easiest call we make in this column.

Pick: Miami 26, New York 14

Sunday, Nov. 29. 2-7-1. NYG -5.5. 3-7. 31. FOX. 56. 1 p.m. ET

If the Giants are going to win the NFC East, it starts here. Daniel Jones and Co. are coming out of the bye week and get Ryan Finley under center for Cincinnati. Spoiler alert, he’s awful. If New York can’t win here, it’s all over, even in that tire fire of a division.

Pick: New York 29, Cincinnati 16

7-3. 35. Sunday, Nov. 29. 7-3. 1 p.m. ET. CBS. 46. IND -4

The most important game of the week. The winner holds a one-game lead in the AFC South. If Indianapolis wins, the Colts are also up a tiebreaker with the season sweep. Tennessee came up huge on Sunday against Baltimore. Can the Titans do it again?

Pick: Indianapolis 26, Tennessee 24