NFL schedule 2021: Biggest game for all 32 teams

AFC South

Houston Texans – Vs. Jacksonville Jaguars

There’s a lot of uncertainty surrounding the Texans this season thanks to the Deshaun Watson situation. Even if Watson suits up for Houston, this team will need a lot to go right to contend, so finding a way to stave off the Jaguars is essential if the Texans want to go anywhere in 2021.

Indianapolis Colts – At Baltimore Ravens

The Colts are looking to prove themselves as a Super Bowl contender in the AFC after making a big trade with the Philadelphia Eagles to land Carson Wentz. One opportunity to prove that status will come when Indianapolis travels to M&T Bank Stadium to take on the Ravens in a game that could have major playoff implications in the AFC.

Jacksonville Jaguars – Vs. New York Jets

The arrival of Trevor Lawrence should certainly help Jacksonville get better but even he can’t turn around a bad Jaguars team overnight. Finding a way to top the Jets, who won just one more game than Jacksonville last season, at home would be a good sign of progress in Urban Meyer’s first season.

Tennessee Titans – Vs. Indianapolis Colts

With the Texans and Jaguars in various stages of disarray, the AFC South will be heavily swayed by the meetings between the Colts and Titans. Tennessee has had its fair share of difficulty dealing with Indianapolis in recent years so picking up a win over the Colts in Nashville would help the Titans out immensely.