2021 NFL schedule release: Picks and predictions for every game

GLENDALE, ARIZONA - AUGUST 20: Quarterback Patrick Mahomes #15 of the Kansas City Chiefs runs up field before the start of the NFL preseason game against the Arizona Cardinals at State Farm Stadium on August 20, 2021 in Glendale, Arizona. The Chiefs defeated the Cardinals 17-10. (Photo by Christian Petersen/Getty Images)
GLENDALE, ARIZONA - AUGUST 20: Quarterback Patrick Mahomes #15 of the Kansas City Chiefs runs up field before the start of the NFL preseason game against the Arizona Cardinals at State Farm Stadium on August 20, 2021 in Glendale, Arizona. The Chiefs defeated the Cardinals 17-10. (Photo by Christian Petersen/Getty Images) /
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KANSAS CITY, MISSOURI – DECEMBER 29: Quarterback Patrick Mahomes #15 of the Kansas City Chiefs passes to tight end Travis Kelce #87 during the 1st quarter of the game against the Los Angeles Chargers at Arrowhead Stadium on December 29, 2019 in Kansas City, Missouri. (Photo by Jamie Squire/Getty Images)
KANSAS CITY, MISSOURI – DECEMBER 29: Quarterback Patrick Mahomes #15 of the Kansas City Chiefs passes to tight end Travis Kelce #87 during the 1st quarter of the game against the Los Angeles Chargers at Arrowhead Stadium on December 29, 2019 in Kansas City, Missouri. (Photo by Jamie Squire/Getty Images) /

AFC Divisional round

124. Final. 20. 46. 31

We saw the Colts come to Arrowhead in 2018 and get clobbered. And while this is a different team, the result is likely similar. Indy doesn’t have the corners to cover Kansas City, or the elite edge rush to hassle Patrick Mahomes. The Chiefs are the better team, and it shows.

53. 27. 16. Final/OT. 24

This would be a phenomenal game. Cleveland is good enough to win, but can they take down Buffalo at home in a raucous atmosphere? These teams are very even, but Allen is the superior player to Mayfield, and ultimately that’s the difference.

NFC Divisional round

36. 34. 49. Final. 31

Earlier in the season, Seattle beat Green Bay at Lambeau Field. The sweep won’t happen. The Seahawks can throw against the Packers, but the opposite is even more true. Without Shaquil Griffin, Seattle is vulnerable and Aaron Rodgers will persistently attack. A high-scoring game ends with the home team moving on.

Final. 28. 48. 30. 51

The dream of repeating dies at SoFi Stadium. The Rams are uniquely built to give the Bucs problems with an interior pass rush and the ability to match up man-on-man outside. It’s hard picking Matthew Stafford to beat Brady, but the ability is there and Los Angeles is just good enough to slow down the Tampa Bay attack.