College football schedule Week 2 picks and predictions for every Top 25 game

Ohio State Buckeyes quarterback CJ Stroud (7) drops to throw during the first quarter of the annual spring game at Ohio Stadium. Mandatory Credit: Joseph Maiorana-USA TODAY Sports
Ohio State Buckeyes quarterback CJ Stroud (7) drops to throw during the first quarter of the annual spring game at Ohio Stadium. Mandatory Credit: Joseph Maiorana-USA TODAY Sports /
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College football schedule for Week 2 features two marquee games and we’ve got college football picks and predictions for every Top 25 game.

Week 1 looked like it would be one of the best opening weeks in recent memory. Now that the dust has settled, we’re all left with one giant question: can Kansas keep the magic going?

There are some other minor questions left in this let-down week of mostly tune-up games. Is Oregon a legit team out of the Pac 12? (Probably not.) Did their near loss in Week 1 wake up Iowa State? Why does beating the No. 12 team make you the No. 11 team? If we keep naming games after mayonnaise, will we keep getting boring defensive battles?

All great questions. Some might be answered this week.

College football Week 2 schedule and predictions

Predicted winner in bold

Friday, Sept. 10 (7:30 p.m. ET)

Kansas at No. 17 Coast Carolina

Saturday, Sept. 11 (12:00 p.m. ET)

No. 12 Oregon at No. 3 Ohio State

Alabama State at No. 25 Auburn

Saturday, Sept. 11 (1:00 p.m. ET)

No. 13 Florida at South Florida

Saturday, Sept. 11 (2:00 p.m. ET)

Middle Tennessee State at No. 19 Virginia Tech

Saturday, Sept. 11 (2:30 p.m. ET)

Toledo at No. 8 Notre Dame

Saturday, Sept. 11 (3:30 p.m. ET)

UAB at No. 2 Georgia

No. 5 Texas A&M at Colorado

Murray State at No.7 Cincinnati

Ball State at No. 11 Penn State

Saturday, Sept. 11 (4:00 p.m. ET)

Mercer at No. 1 Alabama

Saturday, Sept. 11 (4:30 p.m. ET)

No. 10 Iowa at No. 9 Iowa State

Saturday, Sept. 11 (5:00 p.m. ET)

South Carolina State at No. 6 Clemson

Saturday, Sept. 11 (7:00 p.m. ET)

Western Carolina at No. 4 Oklahoma

No. 15 Texas at Arkansas

Easter Michigan at No. 18 Wisconsin

Appalachian State at No. 22 Miami

Saturday, Sept. 11 (7:30 p.m. ET)

Austin Peay at No. 20 Ole Miss

Georgia State at No. 24 North Carolina

Saturday, Sept. 11 (10:15 p.m. ET)

No. 21 Utah at BYU

Saturday, Sept. 11 (10:30 p.m. ET)

Stanford at No. 14 USC

UNLV at No. 23 Arizona State

It’s hard not to go chalk this week, with all the practice games and outmatched ranked meetings. And, in general, it’s not a good sign when the week’s spotlight matchup is set in Iowa. Between Gameday and the Field of Dreams game, this might just be the greatest four-week stretch in the Hawkeye State’s sporting history.

Let’s begin, though, with the other premier game this week, that between Ohio State and Oregon. Even if the Ducks were 100 percent, this would be a huge ask. Now that they are limping into Columbus, it just doesn’t look like Oregon will be able to get the job done. Which is a real shame. College football is better when the Ducks are good.

On the heels of the Ohio State game, conference-mates Iowa will upset Iowa State in Ames. It’s not because Iowa is the No. 9 team in the country (they aren’t). It’s because this is Iowa’s MO. The way this will all play out in the Big Ten is so:

  1. Iowa will beat Iowa State and find themselves in the Top 10;
  2. Undefeated Iowa will host an undefeated Penn State on Oct. 9;
  3. Penn State will beat the pants off of Iowa in an on-paper-it-looks-great game. Not because Penn State is a great team (they aren’t), but because this is what Iowa does;
  4. Undefeated Penn State will play undefeated Ohio State Halloween weekend in another on-paper-it-looks-great game, and the gap between Ohio State and the rest of the Big Ten will be on full display.

Right now, the gap between the Top 6 (Texas A&M excluded, with all due respect) and the rest of the number seven is bigger than the gap between No. 7 (Cincinnati) and No. 25 (Auburn). BYU will drive that point home in a little Pac 12 (getting worked) After Dark action Saturday night.

There shouldn’t be any Montana-over-Washington-type upsets this week. If there is going to be one, though, look out for App State over Miami. The Hurricanes just got embarrassed by Alabama. Let’s see how well they bounce back.

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