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NFL Week 3 2021: Picks and predictions for each game

By Matt Verderame

Sep 19, 2021; Indianapolis, Indiana, USA; Los Angeles Rams quarterback Matthew Stafford (9) drops back to pass the ball in the first quarter against the Indianapolis Colts at Lucas Oil Stadium. Mandatory Credit: Trevor Ruszkowski-USA TODAY Sports
Sep 19, 2021; Indianapolis, Indiana, USA; Los Angeles Rams quarterback Matthew Stafford (9) drops back to pass the ball in the first quarter against the Indianapolis Colts at Lucas Oil Stadium. Mandatory Credit: Trevor Ruszkowski-USA TODAY Sports /
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PITTSBURGH, PENNSYLVANIA – SEPTEMBER 19: Quarterback Derek Carr #4 of the Las Vegas Raiders gestures during the first half of the game against the Pittsburgh Steelers at Heinz Field on September 19, 2021 in Pittsburgh, Pennsylvania. (Photo by Justin K. Aller/Getty Images)
PITTSBURGH, PENNSYLVANIA – SEPTEMBER 19: Quarterback Derek Carr #4 of the Las Vegas Raiders gestures during the first half of the game against the Pittsburgh Steelers at Heinz Field on September 19, 2021 in Pittsburgh, Pennsylvania. (Photo by Justin K. Aller/Getty Images) /

1-1. 59. 2-0. CBS. Sunday, Sept. 26. 28. LV -4. 4:05 p.m. ET

The Raiders might be for real. No, they aren’t winning the Super Bowl, but Derek Carr is playing great ball. Meanwhile, we don’t know who the Dolphins are trotting out under center, and frankly, it doesn’t matter.

Pick: Las Vegas 31, Miami 22

2-0. 45. DEN -10.5. Sunday, Sept. 26. 30. CBS. 4:05 p.m. ET. 0-2

The Jets are absolutely rancid, and now they go to Denver — a brutal place to play — and get to be Denver’s third consecutive victim.

Pick: Denver 23, New York 6

FOX. Sunday, Sept. 26. 4:25 p.m. ET. 1-1. 36. 0-2. 60. SEA -2

The desperation is serious in this one. Minnesota is 0-2, while the Seahawks falling to 1-2 in the NFC West would mean a steep climb. Ultimately, the Vikings will likely find some way to beat themselves.

Pick: Seattle 31, Minnesota 30

2-0. FOX. 2-0. TB -1. 4:25 p.m. ET. 48. Sunday, Sept. 26. 51

Best game of the season so far. Both teams are loaded with star power, but one dirty secret on Tampa Bay? The Bucs have really struggled against the pass so far. Look for Matthew Stafford to unload the ball quick and have Robert Woods and Cooper Kupp make enough plays.

Pick: Los Angeles 34, Tampa Bay 27

8:20 p.m. ET. 49. 2-0. SF -3.5. 1-1. NBC. Sunday, Sept. 26. 42

The Packers were humiliated twice in 2019 by the 49ers, but this San Francisco team has a below-average secondary with a lesser pass rush. It’s a close game, but Aaron Rodgers is the difference.

Pick: Green Bay 27, San Francisco 24

ESPN. 1-1. DAL -4. 1-1. 54. Monday, Sept. 27. 123. 8:15 p.m. ET

The winner could very well be leading the NFC East by itself. Can the Eagles win on the road in Dallas? Of course, but the Cowboys have the better quarterback with a hoard of weapons.

Pick: Dallas 31, Philadelphia 28

Last Week: 12-4
Season: 18-14

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