5 best fantasy football matchups to exploit for Week 4

Sep 19, 2021; Philadelphia, Pennsylvania, USA; Philadelphia Eagles running back Miles Sanders (26) is tackled by ]San Francisco 49ers defensive tackle Javon Kinlaw (99) during the first quarter at Lincoln Financial Field. Mandatory Credit: Eric Hartline-USA TODAY Sports
Sep 19, 2021; Philadelphia, Pennsylvania, USA; Philadelphia Eagles running back Miles Sanders (26) is tackled by ]San Francisco 49ers defensive tackle Javon Kinlaw (99) during the first quarter at Lincoln Financial Field. Mandatory Credit: Eric Hartline-USA TODAY Sports /
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Sep 26, 2021; Inglewood, California, USA; Los Angeles Rams quarterback Matthew Stafford (9) sets to pass in the first half of the game against the Tampa Bay Buccaneers at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-USA TODAY Sports
Sep 26, 2021; Inglewood, California, USA; Los Angeles Rams quarterback Matthew Stafford (9) sets to pass in the first half of the game against the Tampa Bay Buccaneers at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-USA TODAY Sports /

4. QB Matthew Stafford vs. the Arizona Cardinals

Matthew Stafford has been playing at an MVP level through three games with the Rams. He’s fifth in the league in passing yards with 942 and second in touchdowns with nine. He’s also second in quarterback rating behind Russell Wilson.

Stafford’s Week 4 matchup with the Cardinals presents a blowup spot. The Cardinals always seem to find themselves in high-powered games, scoring and giving up points all afternoon. Stafford should have no problem shredding this defense and continuing his hot streak of MVP-level play.

Stafford has overall QB1 upside this week, and I think he’s a guy you should be looking at in a lot of your lineups regardless of how much he costs. In fact, most guys from this game are going to have great fantasy weeks.