5 best fantasy football matchups to exploit for Week 11

Oct 17, 2021; Baltimore, Maryland, USA; Baltimore Ravens wide receiver Marquise Brown (5) is tackled by Los Angeles Chargers free safety Derwin James (33) during the second half at M&T Bank Stadium. Mandatory Credit: Vincent Carchietta-USA TODAY Sports
Oct 17, 2021; Baltimore, Maryland, USA; Baltimore Ravens wide receiver Marquise Brown (5) is tackled by Los Angeles Chargers free safety Derwin James (33) during the second half at M&T Bank Stadium. Mandatory Credit: Vincent Carchietta-USA TODAY Sports /
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November 7, 2021; Santa Clara, California, USA; San Francisco 49ers wide receiver Deebo Samuel (19) is tackled by Arizona Cardinals safety Budda Baker (3) during the third quarter at Levi’s Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports
November 7, 2021; Santa Clara, California, USA; San Francisco 49ers wide receiver Deebo Samuel (19) is tackled by Arizona Cardinals safety Budda Baker (3) during the third quarter at Levi’s Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports /

2. Deebo Samuel, 49ers (vs. Jacksonville Jaguars)

Deebo Samuel is enjoying a third-year breakout while on pace to crush his previous season-highs in receiving. All of this has led to him ascending to a top-five wide receiver in fantasy football. He’s been able to get open at will, both short and long, and is the favorite target of whoever is playing quarterback for the 49ers.

Samuel gets a soft Jacksonville defense that is a middle-of-the-road unit against wide receivers in terms of fantasy points. Samuel has consistently been matchup proof this year, though, but this is one of those games where he could very easily go off for a top-three finish among wideouts.

Samuel is a WR1 most weeks due to his massive target share and ability to get open on every level of the field. He is especially a high-ranked wideout this week, where he has the potential to finish as the overall WR1 in Week 11.