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5 best fantasy football matchups to exploit for Week 13

By Frankie Licausi

Nov 28, 2021; Santa Clara, California, USA; Minnesota Vikings running back Alexander Mattison (25) carries the ball against the San Francisco 49ers during the second quarter at Levi's Stadium. Mandatory Credit: Kelley L Cox-USA TODAY Sports
Nov 28, 2021; Santa Clara, California, USA; Minnesota Vikings running back Alexander Mattison (25) carries the ball against the San Francisco 49ers during the second quarter at Levi's Stadium. Mandatory Credit: Kelley L Cox-USA TODAY Sports /
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Cincinnati Bengals running back Joe Mixon (28) stiff arms Pittsburgh Steelers safety Terrell Edmunds (34) on a carry in the third quarter of the NFL Week 12 game between the Cincinnati Bengals and the Pittsburgh Steelers at Paul Brown Stadium in downtown Cincinnati on Sunday, Nov. 28, 2021. The Bengals beat the Steelers 41-10.Pittsburgh Steelers At Cincinnati Bengals
Cincinnati Bengals running back Joe Mixon (28) stiff arms Pittsburgh Steelers safety Terrell Edmunds (34) on a carry in the third quarter of the NFL Week 12 game between the Cincinnati Bengals and the Pittsburgh Steelers at Paul Brown Stadium in downtown Cincinnati on Sunday, Nov. 28, 2021. The Bengals beat the Steelers 41-10.Pittsburgh Steelers At Cincinnati Bengals /

3. Joe Mixon, Cincinnati Bengals (vs. LAC)

Joe Mixon has been on an absolute tear as of late. His few game stretch of dominance has catapulted him into the top-three of fantasy running backs. His 18.9 carries per game are third in the NFL, and his 84 yards per game are sixth. He’s a set-and-forget running back every week, but he has an especially tasty matchup this week against the Chargers.

The Chargers allow the most rushing yards per game at 145.3, and that has translated over to fantasy points, as they allow the fourth-most fantasy points to running backs. Mixon has elite volume each week and has overall RB1 upside in his easy Week 13 matchup. He’s a top-10 lock this week with upside for more.

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