The 49ers have a chance to take a big step towards the playoffs with a win over the Falcons. Atlanta, meanwhile, could vault over San Francisco by pulling the upset.
Pick: San Francisco 28, Atlanta 20
Whoever loses this is effectively finished, unless the Bengals can find a way to win the AFC North. Cincinnati has picked a bad time to go cold, but it’s also the more talented team.
Pick: Cincinnati 25, Denver 23
If the Rams can’t beat the Seahawks at home, it’s time to give it up. Los Angeles needs a win to keep strong in the postseason picture.
Pick: Los Angeles 32, Seattle 26
This is going to be a blowout. The Saints have absolutely no offense at this point due to injuries, while the Buccaneers are clicking. Expect Tom Brady and Co. to get revenge in a big way.
Pick: Tampa Bay 30, New Orleans 18
This ought to be fun. Kirk Cousins and Matt Nagy squaring off on primetime. Get the popcorn, make sure it’s 350 degrees and slathered in piping-hot butter, and slam your eyes into it.
Pick: Minnesota 23, Chicago 20
Last Week: 11-2
Season: 131-75