2022 NFL Schedule Release: Picks and predictions for every game

KANSAS CITY, MISSOURI - JANUARY 23: Josh Allen #17 of the Buffalo Bills takes the field prior to the AFC Divisional Playoff game against the Kansas City Chiefs at Arrowhead Stadium on January 23, 2022 in Kansas City, Missouri. (Photo by David Eulitt/Getty Images)
KANSAS CITY, MISSOURI - JANUARY 23: Josh Allen #17 of the Buffalo Bills takes the field prior to the AFC Divisional Playoff game against the Kansas City Chiefs at Arrowhead Stadium on January 23, 2022 in Kansas City, Missouri. (Photo by David Eulitt/Getty Images) /
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Cincinnati Bengals wide receiver Ja’Marr Chase. (Getty Images)
Cincinnati Bengals wide receiver Ja’Marr Chase. (Getty Images) /

Week 6

Thursday Night Football

23. . 57. 58. . 24. .

Sunday afternoon

31. 42. . . . . 13. 44

52. . 46. . 24. . 23.

27. 59. . . . . 23. 60

. . 26. . 31. 31. . 14

. 55. . . 27. 48. 21.

56. . . 34. . 27. 15.

19. . . 30. . 37. 49.

53. . . 20. 31. 47. .

18. 87. . . 51. 28. .

36. . 25. 32. . 28. .

27. 124. . . . . 33. 16

Sunday Night Football

22. 123. 30. . . 54. .

Monday Night Football

45. . 30. 13. . . . 28

Byes: Titans, Raiders, Lions, Texans

Game of the Week: Buffalo Bills at Kansas City Chiefs

If you polled most fans, this is the game of the year. Buffalo and Kansas City gave us an all-time, instant classic in the AFC Divisionals last season, forever to be known as 13 Seconds.

Coming into the year, Buffalo is the lone favorite to win Super Bowl LVII, having loaded up on defense with Von Miller coming off the edge. The Bills, though, need to prove their can get past Kansas City, who has ended their season each of the last two years at Arrowhead. However, Buffalo did break through against the Chiefs during the regular season in 2021, pummeling them in Week 5 on Sunday Night Football.

In an odd way, this is the rare game with both teams having plenty to prove. After years of being the obvious favorite in the AFC, Kansas City is now being grouped into the mix, with some believing it won’t make the postseason. The Chiefs have undergone a significant facelift this offseason, trading receiver Tyreek Hill and allowing safety Tyrann Mathieu to leave in free agency. If they beat Buffalo, it would appear Kansas City isn’t only a contender, but perhaps the favorite once more.

Also, the winner might very well host the rematch in January.