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5 best fantasy football matchups to exploit for Week 10

By Frankie Licausi

Nov 15, 2020; Detroit, Michigan, USA; Detroit Lions running back DÕAndre Swift (32) leaps over Washington Football Team safety Deshazor Everett (22) during the first quarter at Ford Field. Mandatory Credit: Tim Fuller-USA TODAY Sports
Nov 15, 2020; Detroit, Michigan, USA; Detroit Lions running back DÕAndre Swift (32) leaps over Washington Football Team safety Deshazor Everett (22) during the first quarter at Ford Field. Mandatory Credit: Tim Fuller-USA TODAY Sports /
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Oct 30, 2022; Seattle, Washington, USA; New York Giants running back Saquon Barkley (26) returns to the bench after rushing for a touchdown against the Seattle Seahawks during the second quarter at Lumen Field. Mandatory Credit: Joe Nicholson-USA TODAY Sports
Oct 30, 2022; Seattle, Washington, USA; New York Giants running back Saquon Barkley (26) returns to the bench after rushing for a touchdown against the Seattle Seahawks during the second quarter at Lumen Field. Mandatory Credit: Joe Nicholson-USA TODAY Sports /

1. Saquon Barkley, RB, New York Giants (vs. HOU)

The likely Comeback Player of the Year has been an absolute steal for fantasy managers who took a chance on him, as he fell to at least the second round in most August drafts.

Saquon Barkley has been right there in the conversation for overall RB1 in fantasy football. He’s been carrying the Giants offense and looks poised for a big payday this offseason, whether it’s New York or another team.

Barkley has been matchup-proof this season, but this matchup is too good to pass up on in all aspects of fantasy football. The best running back in fantasy going up against the worst defense in the NFL in terms of fantasy points per game allowed to running backs.

Barkley has a chance to go absolutely ballistic in this one. Joe Mixon had a five-touchdown performance in Week 9. Barkley has a chance to do something similar here.

Next. 5 breakout fantasy football stars to pick up for Week 10. dark

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