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5 best fantasy football matchups to exploit for Week 16

By Frankie Licausi

Dec 18, 2022; Landover, Maryland, USA; New York Giants quarterback Daniel Jones (8) passes the ball as Washington Commanders safety Kamren Curl (31) defends during the third quarter at FedExField. Mandatory Credit: Geoff Burke-USA TODAY Sports
Dec 18, 2022; Landover, Maryland, USA; New York Giants quarterback Daniel Jones (8) passes the ball as Washington Commanders safety Kamren Curl (31) defends during the third quarter at FedExField. Mandatory Credit: Geoff Burke-USA TODAY Sports /
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Dec 18, 2022; Houston, Texas, USA; Kansas City Chiefs running back Isiah Pacheco (10) in action during the game against the Houston Texans at NRG Stadium. Mandatory Credit: Troy Taormina-USA TODAY Sports
Dec 18, 2022; Houston, Texas, USA; Kansas City Chiefs running back Isiah Pacheco (10) in action during the game against the Houston Texans at NRG Stadium. Mandatory Credit: Troy Taormina-USA TODAY Sports /

Best matchups for fantasy football Week 16: 2. Isiah Pacheco, RB, Kansas City Chiefs (vs. SEA)

Isiah Pacheco had his best matchup of the year last week against Houston, and it’s fair to say it was a disappointment. He ran 15 times for 86 yards but was benched for a while due to a lost fumble and miscues in pass protection. The Chiefs also made the game way closer than it needed to be, allowing Jerick McKinnon to again have a better fantasy day.

The Chiefs still believe in Pacheco as their early-down back, and that’s been proven as of late as he’s had no fewer than 13 carries in a game since Week 9. The Chiefs struggling against bad teams and ultimate commitment to the pass is why Pacheco can’t be a top-10 running back.

He can, however, have pop weeks like he did in Week 11, going 15 for 107 against the Chargers. This week, his matchup against Seattle’s second-worst run defense provides another opportunity to do so. He remains a must-start at the most important position in fantasy football.

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