College Football Teams on Upset Alert for Week 4: Roundtable

Wake Forest is looking to upset Virginia in Week 4.
Wake Forest is looking to upset Virginia in Week 4. / Reinhold Matay-USA TODAY Sports
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Looking for the perfect upset pick for Week 4 of the college football season? You came to the right place. 

Every week here at BetSided, our editors are crunching the numbers to find the best upsets on the slate to help you cash in on some favorable odds.

A 2-2 Week 3 now has our crew at 7-4 on the season, and there are plenty more matchups for us to look at heading into Week 4.

Last week, the BYU Cougars upset Arizona State at home (+150), and Louisville (+215) took down UCF for our two winners. West Virginia hung on at home against Virginia Tech and Notre Dame took care of business against Purdue giving our team a 2-2 week at straight up upsets, but we’re looking to improve that record in Week 4.

So without further ado, our best upset picks for this week’s college football slate with all odds via WynnBET Sportsbook:

Wake Forest (+160) Upsets Virginia

This is a fantastic matchup for Wake Forest when you look at the strengths and weaknesses of both teams.

Wake Forest loves to run the ball, as 60.37% of its plays are rushing plays. This will bode well for the Demon Deacons as Virginia has allowed teams to gain 6.9 yards per carry against it which is the fourth-worst mark in the entire country.

On the flip side, Virginia is a pass-first team offensively as 64.52% of its called plays this season have been pass plays. This fits right into Wake Forest's hands as it ranks 24th in the country in opponent yards per pass attempt, giving up only an average of 5.9 yards per pass.

Give me the Demon Deacons as road underdogs! -- Iain MacMillan


Wake Forest deserves a little bit of respect this week, and I’m going to be the one to give it to the Demon Deacons. Wake Forest blew the doors off of Florida State last week and looked impressive from start to finish. The Demon Deacons are 1-2 against the spread this season, but are averaging 38.5 points per game (against FBS teams). 

Virginia is also a high scoring team, but I’m siding with the Demon Deacons because of their defense. Wake Forest has forced nine turnovers in three games this year and that will bode well against a Virginia team that is giving the ball away twice a game. The Demon Deacons are +160 on the moneyline and I expect them to cash on those odds. -- Donnavan Smoot

No. 12 Notre Dame (+195) Upsets No. 18 Wisconsin

I know, I know Notre Dame has not looked good this season. The Fighting Irish narrowly escaped Florida State and Toledo in the first two weeks of the season before having a little easier of a time with the Purdue Boilermakers in Week 3. 

Now, they get their first AP Top 25 matchup in a neutral site game at Soldier Field against the Wisconsin Badgers. And they’re going to get the win. 

FanSided's College Football Insider Patrick Schmidt isn't as confident in the Fighting Irish, but I'm going to fade him with my pick this week.

Look, Notre Dame has not looked good, especially defensively, but it took a step in the right direction last week holding Purdue to 13 points. The rushing defense (148.3) is a concern against a Badgers team that loves to move the ball on the ground, but I think this matchup comes down to the quarterbacks. 

Graham Mertz has been pedestrian at best for Wisconsin, throwing for just 326 yards and two picks in the team’s first two games against Penn State and Eastern Michigan. Call me crazy, but a 34-7 win over Eastern Michigan hasn’t exactly restored my confidence in a Badgers team that scored 10 points against Penn State. 

Plus, this is a revenge game for Jack Coan. The former Wisconsin quarterback gets a chance to show the Badgers what they’re missing after he chose to use his final year of eligibility at Notre Dame. This game means a hell of a lot more for Notre Dame’s chances of making the College Football Playoff, and I think it pulls off the upset. -- Peter Dewey

Western Kentucky (+280) Upsets Indiana

You could not draw up a worse spot for Indiana. Not only did they squander a double digit lead at home to top-10 Cincinnati in hopes of getting their season back on track, they now have to go on the road to face a Western Kentucky team coming off of a bye in a night game.

With the only Power 5 opponent on tap for this season, this is WKU’s Super Bowl and the coming out party for Houston Baptist transfer Bailey Zappe. Zappe, along with offensive coordinator Zach Kittley and his top three receivers from HBU, joined Western Kentucky in the offseason and have installed their air raid offense.

I’m struggling to see IU getting up for this game and being well prepared to defend this high volume passing attack. Give me Zappe under the lights. -- Reed Wallach

San Jose State (+125) Upsets Western Michigan

Here come the mighty Broncos as they triumphantly return home after a monster 44-41 win over Pitt, the first Power 5 victory under Tim Lester in his fifth season.

The fun will unfortunately be short lived.

San Jose State’s an experienced team that played a formidable USC team in its second game (the Trojans’ season opener), and just beat Hawaii on its home field last week after taking a week off. San Jose State is also projected to finish third in the Mountain West behind Boise State and Fresno State, who have each picked up quality wins so far this year.

Normally I’d have some concern about back-to-back long road trips, but not after the break the Spartans had a week ago. They’re well-balanced on offense with Nick Starkel completing six of his touchdowns to five different receivers, and running back Tyler Nevens needs more carries after averaging 5.5 yards a pop through their first three games.

Meanwhile, it’s a perfect let down spot for Western Michigan, and to make matters worse, the Broncos won’t have their head coach on the sidelines due to a COVID-19 breakthrough case. The last time I bet on a team who lost their coach due to a COVID, my Louisville +10.5 bet against Ole Miss in Week 1 went up in smoke from the moment the game started. I don’t expect this bet to spontaneously combust until at least much later… I hope. -- Ben Heisler


Upset picks to date:

LAST WEEK: 2-2

SEASON RECORD: 7-4


Think one of these underdogs has what it takes to pull off the upset? Get in the action at WynnBET!