NFL Week 4 2021: Picks and predictions for each game

Green Bay Packers quarterback Aaron Rodgers. (Cary Edmondson-USA TODAY Sports)
Green Bay Packers quarterback Aaron Rodgers. (Cary Edmondson-USA TODAY Sports) /
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Sep 26, 2021; Inglewood, California, USA; Los Angeles Rams defensive end Aaron Donald (99) is all smiles as he gestures to the crowd I the fourth quarter against the Tampa Bay Buccaneers at SoFi Stadium. Mandatory Credit: Robert Hanashiro-USA TODAY Sports
Sep 26, 2021; Inglewood, California, USA; Los Angeles Rams defensive end Aaron Donald (99) is all smiles as he gestures to the crowd I the fourth quarter against the Tampa Bay Buccaneers at SoFi Stadium. Mandatory Credit: Robert Hanashiro-USA TODAY Sports /

32. Sunday, Oct. 3. 51. 3-0. LAR -4.5. 4:05 p.m. ET. FOX. 3-0

Great game. The Rams and Cardinals are two of four unbeaten teams in the league, and while Los Angeles appear the best in football, Kyler Murray and his weapons are capable of pulling the upset. Should be a barnburner.

Pick: Los Angeles 30, Arizona 24

36. 42. SF -2.5. 4:05 p.m. ET. 1-2. FOX. Sunday, Oct. 3. 2-1

Can the Seahawks stop Kyle Shanahan’s offense? The guess here is no. If Seattle wins, it’ll be because Russell Wilson enters God mode for four quarters.

Pick: San Francisco 32, Seattle 30

2-1. CBS. PICK'EM. 4:25 p.m. ET. 26. Sunday, Oct. 3. 3-0. 45

The Ravens are a huge, huge step up in class from Denver’s first three opponents in the Jets, Giants and Jaguars. Baltimore will be challenged by the altitude and crowd noise, but it’s been in tougher spots before.

Pick: Baltimore 25, Denver 20

2-1. 49. GB -6.5. 55. Sunday, Oct. 3. 4:25 p.m. ET. 1-2. CBS

The Steelers have no offense. That’s a tough way to go into Lambeau Field for a date with Aaron Rodgers and the Packers. Look for Green Bay’s defense to feast.

Pick: Green Bay 26, Pittsburgh 18

Sunday, Oct. 3. 47. 2-1. 48. NBC. 1-2. TB -7. 8:20 p.m. ET

Tom Brady returns to Foxboro. He’s not losing this game, no matter what Bill Belichick throws at him.

Pick: Tampa Bay 29, New England 17

28. Monday, Oct. 4. 2-1. 8:15 p.m. ET. 3-0. ESPN. 13. LAC -3.5

The Raiders are unbeaten and yet Vegas sees them as a considerable underdog here. Las Vegas is off to a hot start, but the Chargers are more talented on both sides of the ball.

Pick: Los Angeles 28, Las Vegas 23

Last Week: 11-5
Season: 29-19