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DraftKings NFL 2021: Best lineup for Week 12

By Frankie Licausi

Nov 21, 2021; Charlotte, North Carolina, USA; Carolina Panthers quarterback Cam Newton (1) looks to pass in the fourth quarter at Bank of America Stadium. Mandatory Credit: Bob Donnan-USA TODAY Sports
Nov 21, 2021; Charlotte, North Carolina, USA; Carolina Panthers quarterback Cam Newton (1) looks to pass in the fourth quarter at Bank of America Stadium. Mandatory Credit: Bob Donnan-USA TODAY Sports /
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Nov 21, 2021; Paradise, Nevada, USA; Cincinnati Bengals running back Joe Mixon (28) celebrates after scoring on a 20-yard touchdown run against the Las Vegas Raiders in the second half at Allegiant Stadium. Mandatory Credit: Kirby Lee-USA TODAY Sports
Nov 21, 2021; Paradise, Nevada, USA; Cincinnati Bengals running back Joe Mixon (28) celebrates after scoring on a 20-yard touchdown run against the Las Vegas Raiders in the second half at Allegiant Stadium. Mandatory Credit: Kirby Lee-USA TODAY Sports /

Running Back 1: Joe Mixon, Cincinnati Bengals ($7,500)

Joe Mixon had an monster day in Week 11, finishing as the RB4 in PPR leagues. He rushed 30 times for 123 yards and two touchdowns. Any running back getting that kind of workload is almost guaranteed production, and that’s hard to come by in fantasy football.

Mixon is going up against the Pittsburg Steelers, who give up the 12th-most fantasy points to running backs and are the 26th-ranked rushing defense through Week 11. Needless to say, Mixon is set up for another monster day, and should lead our rushing corps in points.

Running Back 2: James Robinson, Jacksonville Jaguars ($6,200)

James Robinson has returned from a brief stint with an injury, assuming the workhorse back role for Jacksonville. Overall in 2021, he’s the 14th running back in fantasy points, and this can largely be due to his bye week and his injury coming right around the same time. He was on a complete tear before injury, and he’s likely going to return to that form this week.

Robinson and the Jags get the Atlanta Falcons, who allow the fifth-most fantasy points to running backs, and allow 123.3 rushing yards per game. Robinson will feast this week and has top-five upside.