5 best fantasy football matchups to exploit for Week 16

Minnesota Vikings wide receiver Justin Jefferson. (Brace Hemmelgarn-USA TODAY Sports)
Minnesota Vikings wide receiver Justin Jefferson. (Brace Hemmelgarn-USA TODAY Sports) /
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Dec 12, 2021; Cincinnati, Ohio, USA; San Francisco 49ers wide receiver Deebo Samuel (19) runs in for the touchdown during the second quarter against the Cincinnati Bengals at Paul Brown Stadium. Mandatory Credit: Joseph Maiorana-USA TODAY Sports
Dec 12, 2021; Cincinnati, Ohio, USA; San Francisco 49ers wide receiver Deebo Samuel (19) runs in for the touchdown during the second quarter against the Cincinnati Bengals at Paul Brown Stadium. Mandatory Credit: Joseph Maiorana-USA TODAY Sports /

3. Deebo Samuel, San Francisco 49ers (vs. TEN)

Here’s a crazy stat for you: Since Week 11, Deebo Samuel is fantasy’s WR14 in PPR leagues. Through those four games (he missed Week 13 with injury), he’s only had seven catches for 109 yards. He’s become a revelation for San Francisco on the ground, as he now leads the team in rushing touchdowns. Head Coach Kyle Shanahan hasn’t been afraid to get Samuel the ball in any way he can, and he’s en route to becoming a position-less player, à la Cordarrelle Patterson.

Samuel is figuring out how to manufacture yards, scores, and mounds of fantasy points for his managers regardless of how it happens. This week, Samuel gets a vanilla matchup with the Tennessee Titans, who have often been gauged by opposing wideouts this season. They allow the third-most fantasy points to receivers, so expect Samuel to continue his fantasy dominance yet again this week when his fantasy managers need it most.