32 NFL Bets to Make Before the Season Starts (One Bet for Every Team)

The NFL season is officially here. Training camps are open, players are being hyped up every day by their coaches and every team has all the potential in the world. 

To celebrate the NFL being back, the BetSided staff has picked their best bet for all 32 NFL teams. These bets range from win totals, to player props to playoff finishes. 

There’s so much to bet on this NFL season, so let’s go through the best bets for all 32 teams. 

NFC East Best Bets 

Philadelphia Eagles - Win the NFC East (+165) 

Yes, this is how we’re starting this portion of the best bets. The Eagles have the best roster in the division and have a case to be one of the top five rosters in the league. Philadelphia addressed a lot of its needs in the offseason. The Eagles bolstered the passing attack by trading for A.J. Brown, signed James Bradberry to help out Darius Slay and drafted Jordan Davis and Nakobe Dean to fortify the front seven.

The key to this will be Jalen Hurts’ progression. Still, Hurts was a below average passer last season and the Eagles still managed to win nine games. If Hurts takes a tiny leap, the Eagles can barrel through their second easiest schedule. – Donnavan Smoot

Dallas Cowboys – CeeDee Lamb OVER 1175.5 Receiving Yards (-120) 

Even as an Eagles fan, this is my favorite bet in the division. I also went to the University of Texas, so I’ve seen how devastating CeeDee Lamb can be for years now. 

The Cowboys traded away Amari Cooper, leaving Lamb as the No. 1 receiver. With Michael Gallup and James Washington hurt, Lamb is set to see insane volume. He was 75 yards away from clearing this line last season, and didn’t even play all 17 games. 

This is Lamb’s year. – Donnavan Smoot

Washington Commanders – Carson Wentz UNDER 3,550.5 Passing Yards (-110) 

Wentz has only cleared this line three times in his six-year career, and there is reason to fade him in 2022. 

Even in a great situation like Indianapolis, Wentz barely cleared this line by 63 yards. The Commanders’ offense will be less potent and have a worse offensive line. 

I don’t expect Wentz to be efficient – or potentially last the entire year. – Donnavan Smoot

New York Giants  – Daniel Jones OVER 11.5 Interceptions (-110) 

Jones cleared this in his rookie season, and has flirted with it in the last two seasons. The main reason why is because he hasn’t been able to be healthy. However, when he’s on the field, Jones throws interceptions. In 38 career games, Jones has thrown at least one interception in half of them. 

If Jones stays healthy, I expect him to make mistakes – as he’s shown he will through three years. – Donnavan Smoot

NFC South Best Bets

Tampa Bay Buccaneers – Win the NFC +330 

The NFC has a lot of “good” teams, but in my opinion, only two “great” teams. The defending Super Bowl champion Rams are certainly one of them, and the other, is the Tampa Bay Buccaneers.

Others might argue the Packers are in that category as well, but I have to see who Aaron Rodgers will be throwing to now that Davante Adams is in Las Vegas.

The Buccaneers had a disastrous start to their playoff game against the Rams. They almost completed the comeback, but fell short. Nothing makes me believe they can’t get back to the postseason and take a run at the Super Bowl once again.

 Even if Tom Brady takes a step back this year, their defense is good enough to carry them. I have concerns about whoever they’d face in the Super Bowl, but I like them to win the NFC at +330. – Iain MacMillan

New Orleans Saints – Jameis Winston Comeback Player of the Year +500

There are only a handful of good candidates for this year’s Comeback Player of the Year award. Two of the top three are running backs Derrick Henry and Christian McCaffrey, but a running back hasn’t won the award since 2001.

That makes Jameis Winston a prime candidate after he tore his ACL and MCL in Week 8.

Winston was having an extremely good year up until the injury, and he had seemingly fixed his interception problem he suffered throughout his career. He racked up 1,170 passing yards, 14 touchdowns, and only three interceptions before his injury. If he can stay healthy this season, he’s in a good spot to win this award. – Iain MacMillan

Carolina Panthers – UNDER 6.5 Wins -110

To be fair, it’s pure speculation, but it seems like head coach Matt Rhule is longing for his days as a college coach and the organization might be in a downward spiral.

Sure, they have Christian McCaffrey on offense, but that’s just about it. If he does get hurt for the third straight year, they’re in deep trouble. Sam Darnold isn’t the answer at quarterback, and Baker Mayfield has had a rough training camp so far.

I think it’s going to be a bad year in Carolina. – Iain MacMillan

Atlanta Falcons – Drake London to Win Offensive Rookie of the Year +800

Drake London will enter the Falcons offense and immediately be the primary target out wide. The USC product was selected eighth overall by Atlanta, and all reports indicate that he’s pro-ready.

The only question regarding him winning Offensive Rookie of the Year, is if he’s going to have a quarterback that will be able to effectively get him the ball. Whether it’s Marcus Mariota or Desmond Ridder, the Falcons aren’t exactly boasting an All-Star arm under center.

Still, unless you want to take the UNDER on the Falcons win total, this is one of the few good bets you can make regarding this team in 2022. – Iain MacMillan

NFC West Best Bets

Los Angeles Rams – Cooper Kupp Most Receptions (+450) 

Yes, this is a square play, but it’s the right play if you want to back a Kupp prop this season. 

The reigning Super Bowl MVP made 145 catches last season on 191 targets, which was 22 more catches than the next closest player last season. The difference between Kupp and the No. 3 player in receptions last season, Tyreek Hill, was 34 receptions!

Kupp is easily Matthew Stafford’s favorite target, and I think this is a crazy value for him at +450 to come close to repeating last season’s output. – Peter Dewey

San Francisco 49ers – Trey Lance OVER 5.5 Rushing Touchdowns (-120) 

I am a little skeptical about how Trey Lance will look this season, but Kyle Shanahan had no problem using his dynamic quarterback in the red zone last year or in the ground game (38 carries in six games, two starts). 

When you look back at some of the rushing touchdown numbers by quarterbacks in recent years, 5.5 seems a little low with Lance’s ability on the ground. Kyle Murray, Cam Newton, Jalen Hurts, Josh Allen and Tayson Hill have all rushed for at least eight scores in a single season over the past two campaigns, so I think Lance can push that category on the ground this year, especially if Shanahan tries to get creative with him in the red zone. – Peter Dewey

Arizona Cardinals – Kyler Murray UNDER 25.5 Touchdowns (-110) 

Kyler Murray has a fresh new contract, but he’s also going to be without his No. 1 receiver, DeAndre Hopkins for six weeks due to a PED suspension. 

In his first three NFL seasons, Murray has thrown for 20, 26 and 24 touchdowns, and he showed last year that he can be prone to injuries. With fewer options on the outside after Christian Kirk also left in free agency, Murray may need to do more on the ground early in the season. 

Also, the Cardinals showed they love James Conner in the red zone last season, so I wouldn't be shocked if there aren’t many easy short TD passes for Murray until Hopkins returns. – Peter Dewey

Seattle Seahawks – Rashaad Penny OVER 800.5 Rushing Yards (-115)

I think this line is a huge value on Penny, who started five games and played in 10 for Seattle last season, carrying the ball 119 times for 749 yards and six touchdowns. 

Penny was a revelation for Seattle last season, and with Chris Carson retiring, I think he has a good chance to clear this line, even with Kenneth Walker III also in the backfield. 

I’d expect the Seahawks to lean on their running game with Geno Smith and Drew Lock fighting for the starting quarterback job, and Penny has been really efficient when healthy, averaging 5.6 yards per carry for his career. 

If Penny can stay healthy and play in close to 17 games, he should easily surpass this line with a similar workload to last season. – Peter Dewey

NFC North Best Bets

Green Bay Packers – OVER 11 Wins (-110)

Until further notice, the NFC North belongs to Aaron Rodgers and the Packers. Yes, Davante Adams is gone, but Aaron Rodgers is still there with an elite defense. Rodgers has the ability to make everyone around him better, and that’s exactly what he’ll do. On top of that, the combination of A.J. Dillon and Aaron Jones will take a load off of Rodgers’ shoulders. 

They should run through the division as usual and go at least .500 for the rest of their schedule. – Donnavan Smoot

Minnesota Vikings – Justin Jefferson OVER 1,350.5 Receiving Yards (-115)

Jefferson is going to have the best receiving season in the league this year. He’s cleared this mark in both of his two years in the league and his role is only growing bigger. With Adam Thielen declining, Jefferson is stepping up and taking over. 

Jefferson took a step back in catch percentage last season, which means that he can still get more efficient. With the amount of targets he’s going to see, there isn’t any doubt that Jefferson can keep pace with what he’s done so far in the league. – Donnavan Smoot

Detroit Lions – OVER 5.5 Wins (-175)

I feel like I’m a little more bullish on the Lions than most people, so I have them hitting the OVER on this win total. Detroit for all of its tough losses last season, played hard and was in several games down the stretch. With Dan Campbell entering his second season, it’s clear the players are buying in, which always helps the rebuilding process. 

Detroit has playmakers on offense, as well. D’Andre Swift is one of the most versatile backs in the league, Amon-Ra St. Brown came on strongly at the end of last season and the Lions will get Jameson Williams in the second half of the season. Jared Goff, and I understand this might be a lot to ask of him, just needs to be even slightly below average for the Lions to be competent. – Donnavan Smoot

Chicago Bears – UNDER 6.5 Wins (-150)

There is absolutely no way the Bears reach this line. Chicago’s offensive line is still a mess, its receiving corps might be the worst in the league and the Bears lost Khalil Mack and Akeem Hicks this offseason.

The Bears might be in the running for the No. 1 pick in the draft next season. Although I like Justin Fields as a prospect, this is asking way too much from him. Chicago should consider itself lucky if it finishes anything other than last in the division. – Donnavan Smoot

AFC East Best Bets 

Buffalo Bills – Gabriel Davis OVER 60.5 Receptions (-110)

There’s a lot of ways you can bet on the Bills this season, but all of their props are either way too far in the future to be a “best bet” or have no value. 

With that in mind, I’m looking forward to Gabriel Davis to have a breakout season. The Bills are one of the most pass-heavy offenses in the league and they just lost Cole Beasley and Emmanuel Sanders. There’s a giant hole at the No. 2 receiver spot and Davis fits it perfectly. He had 35 receptions last season as the No. 4 receiver and only started in four games. 

We saw how talented he is in the playoffs. In just two games, Davis had 10 catches. Put that over an entire season and 60.5 looks like a steal. – Donnavan Smoot

New York Jets – Elijah Moore OVER 64.5 Receptions (-110)

This is another bet on a receiver to have a breakout season. Moore was touted as one of the best receivers in the draft last year and expectations were high. However, he only played in 11 games and the Jets offense as a whole disappointed. 

In Year 2, he and Zach Wilson should be better and healthier. Moore had 77 targets in 11 games last year. If we bump that up by one target per game and extrapolate it to the entire season, Moore is in line for well over 110 targets this season. The Jets are going to put him in a position to succeed and I trust them to feed him. – Donnavan Smoot

Miami Dolphins – Finish Second in AFC East (+175)

Although this bet is somewhat specific, it makes a lot of sense to me. I think we all expect the Bills to win the AFC East. That leaves the door open for the second position. The Jets are still rebuilding and won’t be that good and I’m not too high on the Patriots. 

Miami added one of the best receivers in the league in Tyreek Hill. That’s not only going to help Tua Tagovailoa, but also Jaylen Waddle – who will thrive without the entire defense focusing on him. 

The Dolphins’ defense is still solid and the offense is set to take a leap. At nearly 2/1 odds, I like this bet a lot. – Donnavan Smoot

New England Patriots – UNDER 8.5 Wins (+135)

These are not the Patriots of old. We can’t count on them to win 12 games every season, and I don’t think we can count on them being over .500 every season. New England has the eighth-hardest schedule in the league and it will be a challenge without elite skill players on the outside. 

The Patriots revived their season by winning eight of their middle nine games. You can’t bank on a seven-game winning streak happening every season. Mac Jones still has a lot to prove, and doesn’t have receivers to help. On top of that, the defense lost J.C. Jackson – hurting the secondary. 

There’s too much unknown with the Pats, so I’ll fade them. – Donnavan Smoot

AFC South Best Bets

Indianapolis Colts – Matt Ryan OVER 3,900 Passing Yards (-110)

If Carson Wentz can throw for 3,500 yards in this Colts offense, Matt Ryan can easily push 4,000 yards. The Colts are going to give Ryan the best situation he’s been in since 2016 and I expect Ryan to have a good year. 

While Jonathan Taylor’s presence might scare you from betting the over, don’t expect him to have another 350 carry season now that he has a competent quarterback. – Donnavan Smoot

Tennessee Titans – To Miss the Playoffs  (-120)

Whew, I don’t know where the Titans are going to find sustained success this season. Without A.J. Brown or Julio Jones, they don’t have any other offense plan outside of giving Derrick Henry the ball. 

The Colts are my pick to win the division, which means I expect the Titans to have to get a wild card spot to make the playoffs. The AFC West has four playoff-quality teams alone. When you add that with division winners from across the conference, I see Tennessee on the outside looking in. – Donnavan Smoot

Jacksonville Jaguars – Jaguars OVER 6.5 Wins (+105)

Yes, the team with the worst record in the league in back to back seasons is going to make a jump near .500. The Jaguars have rid themselves of the plague that is Urban Meyer and will finally be able to operate as a real franchise. 

Trevor Lawrence is set to take a step forward in Doug Pederson’s quarterback friendly offense, and the defense will get a boost with Travon Walker’s presence. The AFC South is one of the weaker divisions in the league, so the Jags can steal a few wins there and clear this line. – Donnavan Smoot

Houston Texans – Brandin Cooks OVER 950.5 Receiving Yards (-110)

Cooks has quietly been one of the most consistent receivers in the league. He’s reached over 1,000 yards receiving in six of the seven seasons following his rookie year. The Texans don’t have many weapons on offense, so Cooks sees a lot of volume. He had a career high in targets last season. With Davis Mills still learning the ways of the league, expect him to lean on Cooks to help him out. – Donnavan Smoot

AFC West Best Bets

Kansas City Chiefs – OVER 10.5 Regular Season Wins (-115)

Jump on this line as fast as you possibly can. 

I know the Chiefs lost Tyreek Hill and Tyrann Mathieu in the offseason, but they improved their defense through the draft and free agency, adding impact players such as Trent McDuffie, George Karlaftis and Carlos Dunlap. 

Patrick Mahomes is still the quarterback for this team, which means the offense will still be lethal even without Hill, and JuJu Smith-Schuster, Marquez Valdes-Scantling, Mecole Hardman and Skyy Moore are a more than serviceable group of receivers. 

The biggest thing for me is this: Since Mahomes took over as the Chiefs’ starting quarterback, they have won 12, 12, 14 and 12 games. You mean to tell me, in a 17-game season, that Kansas City can’t win at least 11 in 2022? 

I’m not buying it. The Chiefs are going to smash this win total projections, even in a tough AFC West. – Peter Dewey

Denver Broncos – Jerry Jeudy OVER 905.5 Receiving Yards (-120)

I hope you’re ready for some Jerry Jeudy propaganda, because he’s going to have a huge year in 2022. 

The Broncos lost wideout Tim Patrick for the season due to a torn ACL, but that means more targets for Jeudy, who has already been a favorite target of Russell Wilson in training camp. 

Last season, Jeudy was limited to just 10 games due to injury, but he put up 467 yards on just 56 targets. What may be more impressive is Jeudy is the best WR in the league at creating separation on his routes since entering the NFL.

That’s pretty damn good. With Wilson under center and more targets opened up by the Patrick injury, Jeudy is in line to have a massive 2022 season. He put up 856 yards a rookie with a revolving door at quarterback. He’s going to crush this total in 2022. – Peter Dewey

Los Angeles Chargers – Keenan Allen OVER 100.5 Catches (+100)

It’s hard to deny how consistent Keenan Allen has been the past few seasons, and now he has even more time with star quarterback Justin Herbert to establish some solid chemistry. 

Allen, who caught 106 passes in the 2021 season, has cleared this number in three of the last five years, and he’s had 97 or more catches in each of those seasons. In 2020 he finished with 100 catches, but he played in just 14 games to reach that number. 

We know Brandon Staley’s team is going to be aggressive, and Allen has the benefit of a 17-game season in a division that should be tight, so every game will matter. Allen is averaging nearly 150 targets per season over the last five years. There’s value on this at plus money. – Peter Dewey

Las Vegas Raiders – Las Vegas Raiders to Make the Playoffs (+160)

This is by far the riskiest pick I have in the AFC West, but the Raiders are being disrespected after making the postseason in the 2021 campaign. 

Las Vegas added arguably the best receiver in the NFL in Davante Adams, and it has a new regime at the helm after a ton of team turmoil in 2021. 

Sure, the division is really tough, but all four of these teams could make the playoffs with the three wild card spots. 

I also could see the Raiders making the postseason over Denver or Los Angeles, similar to how it stole a spot from the Chargers last season. Derek Carr deserves more respect than he’s getting, and with the other three teams being favored to make the postseason, this is the best value you’ll get in a division with four quality teams. – Peter Dewey

AFC North Best Bets

Baltimore Ravens – Rashod Bateman OVER 850 Receiving Yards (-110)

With the departures of Hollywood Brown and Sammy Watkins, Bateman is now the No.1 receiver on the depth chart. He’s sure to see an increase in targets and with Lamar Jackson slated to be healthy, that connection is going to be a crucial one for the Ravens offense. 

Brown had over 1,000 yards last season and I’m expecting Bateman to get the same type of workload. Even if he isn’t as efficient, the opportunity will be there. – Donnavan Smoot

Cleveland Browns — Nick Chubb UNDER 10.5 Rushing Touchdowns (-105)

Chubb, as great of a back as he is, has only cleared once in his career. As long as Kareem Hunt is there to share the backfield, I’m not 100% confident in Chubb getting the goal-line touches to clear this. 

Chubb is a methodical runner too, so the long 75-yard touchdowns aren’t really his thing. The Browns are either going to have Deshaun Watson as their quarterback, aiding their passing game, or Jacoby Brissett as their QB, which will hinder the offense as a whole. 

There’s a lot of uncertainty around the Browns this season, but Chubb being a high-volume touchdown scorer has consistently not been a thing. – Donnavan Smoot

Cincinnati Bengals – Joe Mixon UNDER 10.5 Rushing Touchdowns

I’m very skeptical about the Bengals this season, as they overperformed in 2021. One player that really overperformed was Joe Mixon. He hit double-digit touchdowns for the first time in his five year career. The Bengals gave Mixon his biggest workload yet, and I don’t see him being a back to receive close to 300 carries this season. 

Mixon has also shown that he might not be available for the entire season, missing games in four of the five years in his career. Unless the Bengals take another leap offensively, asking Mixon to score over 10 touchdowns is a big ask. – Donnavan Smoot

Pittsburgh Steelers – OVER 7 Wins (-125)

For as long as Mike Tomlin has been the coach of the Steelers, they’ve never had a losing record. Now, you want me to bet against him being three games under .500? 

NOPE. 

The Steelers still have a solid defense, playmakers on the outside, and a young dynamic back in Najee Harris. I understand the AFC North is going to be tough, but the Steelers have had worse teams and done better. – Donnavan Smoot

Follow along with BetSided's picks on Betstamp all season long.