NFL Picks: Our Staff's Best Bets for Week 2

Josh Allen and the Bills are due to bounce back in Week 2.
Josh Allen and the Bills are due to bounce back in Week 2. / Mark Konezny-USA TODAY Sports
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Looking for some NFL picks? Our staff at BetSided has you covered with their best bets for Week 2 of the NFL season.

Last week, our team went a blistering 4-0 with our best bets for Week 1 of the NFL season, and we’re looking to keep things rolling in Week 2.

For even more previews, predictions and analysis, check out our NFL homepage, our College Football page, as well as the full video below.

All odds are courtesy of WynnBET Sportsbook.

New Orleans Saints at Carolina Panthers (-3.0) | Total 44.5

THE PLAYSaints -3.0 (-125)

I’m going to back the Saints. In my opinion this is the easiest bet of the week. 

This offseason, nobody was really talking about the Saints’ defense. Everyone was talking about the Los Angeles Rams defense, the Baltimore Ravens defense and the Pittsburgh Steelers defense. 

The Saints were third in defensive scoring last year and they allowed the second-fewest opponent yards per game. We saw what they did in Week 1 against reigning MVP Aaron Rodgers and the high-powered Packers offense, they kept them to three points! Now they’re going up against the Carolina Panthers and Sam Darnold and they’re only laying three points? Easiest bet of the week, and I love Jameis Winston as well. -- Iain MacMillan

Los Angeles Rams (-3.5) at Indianapolis Colts | Total 48.0

THE PLAYRams -3.5 (-110)

Frank Reich’s teams have been horrible in the first five weeks of the season since he took over as the Colts head coach, going just 7-9 in 16 games. The rest of the time? Indy is 21-12. 

The Colts love to start slow and they started slow at home in Week 1 against the Seattle Seahawks and while it may be a surprise that they come in as such big underdogs, if you look at the Rams under Sean McVay, they are 17-6 straight up as an away favorite. 

Conversely, Reich and the Colts are 0-4 as home underdogs since he took over. The Rams just came off a huge win against the Chicago Bears and put on arguably the best performance of a contender in Week 1, so I like them to keep it going this week. -- Peter Dewey

Buffalo Bills (-3.0) at Miami Dolphins | Total 47.5

THE PLAY: Bills -3.0 (-125)

I’m putting my trust back in the Bills, because I don’t think they’re going to go 0-2. 

You see the way that Dolphins quarterback Tua Tagovailoa looked in Week 1, and I don’t think that he looked great. Also, the Dolphins put up less than 20 points and the Bills put up 16 in their loss to the Steelers. 

I’m very, very confident that the Bills are going to score more than 16 points in Week 2, so I’m going to take them as three-point favorites. -- Donnavan Smoot

Dallas Cowboys at Los Angeles Chargers (-3.5) | Total 54.0

THE PLAYChargers -3.5 (-110)

I like the Chargers as 3.5-point home favorites. I see them being a little undervalued here against a Dallas defense that I wasn’t impressed with in Week 1. I think they got in the cover last week against Tampa Bay due to a lot of turnover luck. I don’t see that happening here against the Chargers offense.

Justin Herbert looked great in Week 1 against Washington even though he didn’t put up a big number on the scoreboard, with 337 yards passing and he looked confident down the stretch. I was honestly impressed with the Chargers as a whole. 

New coach Brandon Staley, last year if you look back to Week 1 when he was the Rams’ defensive coordinator against the Cowboys, he shut down that Dallas offense with Dak Prescott fully healthy. They only scored 17 points on Sunday Night Football in that game. Yes, this Chargers defense isn’t exactly like the Rams of last year, but with Joey Bosa and Derwin James out there I like Brandon Staley to draw up a good gameplan. -- Reed Wallach

Detroit Lions at Green Bay Packers (-11.0) | Total 48.5

THE PLAYPackers -11.0 (-110)

I know it’s usually not a strong idea to take an 11-point favorite after losing by 30 points in Week 1, but it’s Green Bay at home on Monday Night Football in an opportunity for Aaron Rodgers to shake off some of the doubters after an MVP-caliber season. 

The Lions last year did not win a game when they were double-digit underdogs. This is not going to be the week that they pull it off even though the Lions backdoor covered in Week 1 against the San Francisco 49ers. I love this as an opportunity for Green Bay to make a statement. 

Cornerback Jeff Okudah, the Lions No. 3 overall pick from a season ago, is done for a while with an Achilles injury. I think Green Bay makes this very ugly, very quickly. -- Ben Heisler


NFL Best Bets Record

LAST WEEK: 4-0

SEASON RECORD: 4-0


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