Jackson, who continues to start in place of the injured Russell Westrbook, was nine-of-12 from the field. His 27 points was a career-high.
Kevin Durant poured in 21 points, eight assists and seven rebounds and Serge Ibaka scored 17 points, grabbed 11 rebounds, dished out three assists and blocked two shots.
Jeff Green and Avery Bradley scored 19 points apiece to lead the Celtics. Jordan Crawford had 17 points and seven assists and Kris Humphries came off of the bench to score 14 points, grab three rebounds and block three shots.
The Thunder offense was efficient throughout the game and they had 66 points by the end of the first half. For the game, they shot 51.8% from the field (43-of-83), 47.4% from beyond the arc (nine-of-19) and hit 24 of their 31 free throws (77.4%). They also turned the ball over just nine times.
The Thunder are now 27-7 on the season and 4-2 since losing Westbrook. The Celtics are 13-21.