5 NFL teams on upset alert in Week 5

September 13, 2015; Oakland, CA, USA; Cincinnati Bengals quarterback Andy Dalton (14) passes the football before the game against the Oakland Raiders at O.co Coliseum. Mandatory Credit: Kyle Terada-USA TODAY Sports
September 13, 2015; Oakland, CA, USA; Cincinnati Bengals quarterback Andy Dalton (14) passes the football before the game against the Oakland Raiders at O.co Coliseum. Mandatory Credit: Kyle Terada-USA TODAY Sports /
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Oct 4, 2015; Orchard Park, NY, USA; Buffalo Bills running back Karlos Williams (29) celebrates his touchdown against the New York Giants during the second half at Ralph Wilson Stadium. Giants beat the Bills 24-10. Mandatory Credit: Kevin Hoffman-USA TODAY Sports
Oct 4, 2015; Orchard Park, NY, USA; Buffalo Bills running back Karlos Williams (29) celebrates his touchdown against the New York Giants during the second half at Ralph Wilson Stadium. Giants beat the Bills 24-10. Mandatory Credit: Kevin Hoffman-USA TODAY Sports /

2. Buffalo Bills

Speaking of one of the league’s best defenses that got beat by the Giants last week, that team was the Buffalo Bills. They suffered a huge letdown against New York in Week 4 and are now going to be playing on the road against a feisty Tennessee Titans team. Despite the chance to feast on a rookie quarterback, this game has upset written all over it.

For one, Marcus Mariota has looked far more mature than many rookie quarterbacks that we’ve seen in recent years. Meanwhile, the Bills secondary has proven that they are vulnerable for time to time. Mariota, if he’s given or can create time to throw the ball, should have the chance to really move the ball with his arm in this game.

However, the bigger worry for Buffalo is that they are going to have to rely so heavily on Tyrod Taylor in this game. Taylor has been solid, but he’s not an experienced enough quarterback to where you can put too much weight on him in a gameplan. With LeSean McCoy and Karlos Williams both possibly missing this game and likely not being at 100 percent if they do play, the onus of the offense will be on Taylor. I like Taylor, but that more than gives the Titans a shot to win this game along with everything else.

Next: No. 1 Green Bay Packers