Fantasy football-top waiver wire week 16 pickups

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Nov 12, 2015; East Rutherford, NJ, USA; Buffalo Bills running back Karlos Williams (29) celebrates with Buffalo Bills wide receiver Sammy Watkins (14) after scoring a touchdown in the second half at MetLife Stadium. The Bills defeated the Jets 22-17 Mandatory Credit: William Hauser-USA TODAY Sports /

Karlos Williams-RB-Buffalo Bills (35.0%)

LeSean McCoy is officially week-to-week with a torn MCL, but it seems clear he’ll miss at least one game and likely sit out the season finale as well. Buffalo has a pair of running back who will try and step up in his place led my rookie former-Seminole Karlos Williams.

Williams sustained his own injury on Sunday finishing the game “sore” according to coach Rex Ryan. He did complete the game, but only had four carries for 41 yards. If he’s healthy, he should be the biggest beneficiary from Shady’s injury, but that’s a big enough “if” that he drops down the list to this point as a result.

Williams has shown he can produce if he gets the workload, but expect Mike Gillislee to get a larger share of the work if Williams is limited. Williams injury makes him high-risk, high-reward as the Bills finish their season with Cowboys and the Jets.

Next: A rookie WR on the rise after a slow start

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