Final Four 2018 opening betting odds: Villanova, Michigan favored

The point spreads are set for the Final Four and the Villanova Wildcats and Michigan Wolverines are favored to advance to the title game.

After all the buzzer-beaters, countless busted brackets and amazing Sister Jean stories, we’ve arrived at the Final Four of the NCAA Tournament. Loyola was the first to earn their spot in the Final Four after beating Kansas State on Saturday night.

They are the Cinderella story of the tournament as a No. 11 seed. They are on a mission from God as many signs at Loyola games have referenced in a sign of appreciation for team chaplain, 98-year-old nun, Sister Jean.

The Ramblers may have a higher power helping them along, but they’re the underdog when they meet John Beilein’s Michigan Wolverines on Saturday at 6:09 p.m. ET on TBS. According to RJ Bell, the Wolverines are opening as 6-point favorites over the Ramblers.

I think I may have to make a small play on Loyola in this one to cover the spread.

Villanova and Kansas serves as the main event on Saturday night. The game between the two No. 1 seeds is sure to draw big TV ratings and the winner of this game likely will be the prohibitive favorite in the national title game.

The Wildcats open as 5-point favorites over Bill Self’s Jayhawks who beat the Duke Blue Devils in overtime of their Elite 8 matchup in what I believe was the best game of the tournament so far. Villanova won it all two years ago while Self is looking to add a second national title of his own. This spread is too dangerous for me to wager on right now, but I am going to watch the line to see if it moves leading up to their tip on Saturday night. My gut is telling me to roll with Kansas, but I’m torn because Villanova can beat anyone when they’re raining shots from beyond the arc.

Next: 28 Most Memorable Buzzer Beaters in March Madness History

Who are you betting on in the Final Four? Who do you think will be the last team standing and cutting the nets down on Monday night?