College football odds: How to bet every Top 25 game in Week 3

With the college football odds out, here’s how to bet on college football Week 3 games, including the Miami and Louisville game on Saturday night.

After Pac 12 and Big Ten teams were still ranked in the college football Top 25 last week, this week they were removed from the rankings. That means there is a much larger percentage of teams getting ranked every week than a normal year. This gives us a better idea of how to pick games every week when the focus is expanded.

With teams like Ohio State, Wisconsin, Oregon and Penn State off the rankings this week, teams like Baylor, Pitt, and Louisiana-Lafayette have a chance to enter the rankings. The Ragin Cajuns have the biggest win of the season, upsetting Brock Purdy and Iowa State last week.

Now, the teams are mostly past their non-conference schedules and moving towards conference only matchups. There are a few exceptions, but it’s starting to get into the crux of what this season is.

All odds courtesy of the William Hill Sportsbook.

How to bet on college football Week 3 and use the latest college football odds to your favor so you can win some cash betting on these Top 25 games

Syracuse vs. No. 25 Pittsburgh (-22)

The Pittsburgh Panthers is back to having a number next to its name. They still aren’t considered one of the top programs in the country, but with less competition, they can stand out. The Panthers have a lot of returning starters from a team that took Penn State to the limit last season. Syracuse is getting a ton of points here, and the extra point past 21 is scary, but a blowout seems likely.

Pick: Pittsburgh (-22)

No. 23 Appalachian State (-3.5) at Marshall

This one is an interesting matchup of strength versus strength. Marshall used a suffocating defense to help dominate Eastern Kentucky. Meanwhile, Appalachian State put up more than 500 yards in their win versus the Charlotte 49ers. This matchup comes down to freshman quarterback Grant Wells facing his first real test with the Thundering Herd. Despite App. State’s struggles to stop the run, they make just enough plays to win this one by four.

Pick: Appalachian State (-3.5)

No. 19 Louisiana (-16.5) at Georgia State

Louisiana-Lafayette shocked the Big 12 by taking out Iowa State, a team that could have made some noise with a senior quarterback and an interesting set of returning starters. This is one of the strongest teams in the Sun Belt Conference. Georgia State hasn’t played a game this year, and that lack of continuity against a team flying high puts them at an early disadvantage they can’t climb out of.

Pick: Louisiana (-16.5)

No. 17 Miami vs. No. 18 Louisville (-2.5)

This is by far the matchup of the weekend and probably the best game of the early football season. Miami believes the sky is the limit with D’Eriq King, who finds himself third in the Heisman Trophy odds. This one is honestly going to come down to turnovers. As good as King is under center, his decision making isn’t always the best. He could have a back-breaking turnover if he’s not careful. Meanwhile, Louisville fumbled twice (losing one) and Micale Cunningham threw an interception against Western Kentucky. Obviously, it didn’t impact the final score, but those habits die hard. In the end, it feels like a coin flip. In these situations, take the superior talent and take points.

Pick: Miami (+2.5)

No. 14 UCF (-7) at Georgia Tech

The UCF Knights are facing their only Power 5 team this weekend when they face freshman quarterback and reigning ACC Player of the Week Jeff Sims. This game is up I-75 for UCF, who’s looking to take advantage of a year when an undefeated season likely brings them to the College Football Playoff they so desperately wanted. Still, this has trap game written all over it. Georgia Tech was awesome last week against Florida State. UCF hasn’t played yet. If the Yellow Jackets don’t rest on their laurels and focus on the task at hand, they can take advantage of a rusty Knights team.

Pick: Georgia Tech (+7)

Austin Peay vs. No. 13 Cincinnati (-34.5)

This one should be a one-sided affair. There are a lot of sportsbooks that aren’t even taking bets on this game because of the lack of talent on the Austin Peay team. Cincinnati might beat this particular spread by halftime. Cincinnati returns 16 starters. A veteran team like this isn’t going to let the rust hit them against an extremely beatable opponent.

Pick: Cincinnati (-34.5)

Tulsa at No. 11 Oklahoma State (-22.5)

After most of the Big 12 got going last week, one of the most interesting teams in the conference takes the field against a game Tulsa team this week. Chuba Hubbard finally takes the field after an interesting offseason for him. He’s looking to build his resumè as one of the best Oklahoma State running backs in history (which is saying something since Thurman Thomas and Barry Sanders hold most of the records there). Tulsa will score some points, but their defense won’t be able to hold the Cowboys down even with a big spread.

Pick: Oklahoma State (-22.5)

South Florida at No. 7 Notre Dame (-26)

USF is looking to start anew with former Clemson offensive coordinator Jeff Scott. They added this game with Notre Dame this season, which should be a good test for him early in his head coaching tenure. This should be an easy win for a veteran Notre Dame team who’s hoping to get Ian Book going behind an experienced offensive line, but USF will throw the kitchen sink at the Fighting Irish. That helps them beat the spread.

Pick: South Florida (+26)

The Citadel vs. No. 1 Clemson (-45.5)

Trevor Lawrence faces the last non-conference opponent of his star-studded college career. Unfortunately, it’s nothing like Texas A&M, who was their best non-conference opponent last season. The Citadel is a team most probably didn’t remember has a football team. They lost by 21 last week to the USF Bulls in former Clemson coach Jeff Scott’s debut. Clemson could easily more than double that deficit.

Pick: Clemson (-45.5)

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