5 best fantasy football pickups to make for Week 2

Sep 12, 2021; Houston, Texas, USA; Houston Texans running back Mark Ingram (2) runs with the ball as Jacksonville Jaguars defensive back Andrew Wingard (42) attempts to make a tackle during the third quarter at NRG Stadium. Mandatory Credit: Troy Taormina-USA TODAY Sports
Sep 12, 2021; Houston, Texas, USA; Houston Texans running back Mark Ingram (2) runs with the ball as Jacksonville Jaguars defensive back Andrew Wingard (42) attempts to make a tackle during the third quarter at NRG Stadium. Mandatory Credit: Troy Taormina-USA TODAY Sports /
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San Francisco 49ers running back Elijah Mitchell (25) runs by Detroit Lions defensive back Tracy Walker III (21) Sunday, Sept. 12, 2021 at Ford Field.Lions 49ers
San Francisco 49ers running back Elijah Mitchell (25) runs by Detroit Lions defensive back Tracy Walker III (21) Sunday, Sept. 12, 2021 at Ford Field.Lions 49ers /

1. Elijah Mitchell, RB, San Francisco 49ers

One of the big surprises in fantasy circles in Week 1 was when the inactives were named. For the 49ers, it was rookie Trey Sermon — who many thought would lead the backfield — that was named a healthy scratch. Instead, their other rookie Elijah Mitchell was active and blew up as Raheem Mostert suffered what has become an inevitable annual early-season injury.

With Mostert’s departure, Mitchell seized this backfield, rushing 19 times for 104 yards and a touchdown. Not only do the stats look good, but Mitchell himself looked like a good real-life football player, and he’s going to be someone that Kyle Shanahan wants on the field.

Mitchell is a must-add in your fantasy team, and he’ll obviously be a hot commodity. You’ll need to either have a high waiver pick or spend a lot of your FAAB (money to bid on free agents) to get him, depending on what method your league uses.

Mitchell’s potential outcomes range from: back-up who filled in nicely for Mostert but will resume bench duties when Mostert returns, or a guy who just seized a backfield that wants to run the ball all game and could be a potential league-winner for you. Take the gamble on the latter and pick him up.