FanDuel NFL 2021: Best lineup for Week 6

CINCINNATI, OHIO - OCTOBER 10: Davante Adams #17 of the Green Bay Packers against the Cincinnati Bengals at Paul Brown Stadium on October 10, 2021 in Cincinnati, Ohio. (Photo by Andy Lyons/Getty Images)
CINCINNATI, OHIO - OCTOBER 10: Davante Adams #17 of the Green Bay Packers against the Cincinnati Bengals at Paul Brown Stadium on October 10, 2021 in Cincinnati, Ohio. (Photo by Andy Lyons/Getty Images) /
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Credit: Getty Images
Credit: Getty Images /

Running Backs

Darrell Henderson, Los Angeles Rams at New York Giants-$7,300

Sony Michel has taken a role in the Rams’ backfield, but Henderson is clearly the lead back with a touchdown in three of four games this season and over 80 yards on the ground in the last two.

In Week 6 Henderson gets the New York Giants, who are a bottom-10 defense in fantasy points allowed to running backs. Opposing backs have gotten them via ground and air, and Henderson had 11 targets and eight catches in Week 3 and 4 combined.

The Rams are a 9.5-point favorite on Sunday. The Giants might not have quarterback Daniel Jones (concussion), and they won’t have running back Saquon Barkley (ankle). It all points to run-heavy game script late in the game. While Michel may get a share of carries in that scenario, Henderson is the DFS play.

D’Andre Swift, Detroit Lions vs. Cincinnati Bengals-$7,100

Swift is the Lions’ leading receiver (29 catches for 252 yards), with at least 17 touches, over 100 total yards a touchdown in three of five games this season. There’s a case that Jamaal Williams should play more behind or alongside him, but Swift is the best thing going for Detroit’s offense.

In Week 6 the Lions face the Bengals, who are overall mid-pack against running backs in fantasy terms. But they have yielded the second-most targets (51) and tied for the second-most receptions (41) to the position through Week 5. However skewed by Najee Harris in Week 3 (14 catches on 19 targets), that’s the path to extra production for Swift. Don’t ignore players on bad teams, in DFS or season-long, and Swift is a fantastic play in Week 6.