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NFL Week 1 2022: Picks and predictions for every game

By Matt Verderame

Cooper Kupp, Matthew Stafford, Los Angeles Rams. (Mandatory Credit: Mark J. Rebilas-USA TODAY Sports)
Cooper Kupp, Matthew Stafford, Los Angeles Rams. (Mandatory Credit: Mark J. Rebilas-USA TODAY Sports) /
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NASHVILLE, TENNESSEE – JANUARY 22: Derrick Henry #22 takes a hand off from Ryan Tannehill #17 of the Tennessee Titans during a game against the Cincinnati Bengals in the AFC Divisional Playoff game at Nissan Stadium on January 22, 2022 in Nashville, Tennessee. The Bengals defeated the Titans 19-16. (Photo by Wesley Hitt/Getty Images)
NASHVILLE, TENNESSEE – JANUARY 22: Derrick Henry #22 takes a hand off from Ryan Tannehill #17 of the Tennessee Titans during a game against the Cincinnati Bengals in the AFC Divisional Playoff game at Nissan Stadium on January 22, 2022 in Nashville, Tennessee. The Bengals defeated the Titans 19-16. (Photo by Wesley Hitt/Getty Images) /

Sunday, Sept. 11. 4:25 p.m. ET. FOX. 31. 0-0. 35. TEN -5.5. 0-0

The Giants and Titans are both in weird spots. New York is transitioning out of a disastrous run under former general manager Dave Gettleman. Tennessee is trying to contend with a decent defense and no passing game. Still, the Titans are a much better team.

Pick: Tennessee 30, New York 20

GB -1.5. 0-0. 49. FOX. Sunday, Sept. 11. 0-0. 60. 4:25 p.m. ET

This seems like a good time to point out Aaron Rodgers is still great, and the Packers might have an elite defense. Minnesota is good and rapidly improve under new head coach Kevin O’Connell, but Green Bay is the more complete team.

Pick: Green Bay 27, Minnesota 23

Sunday, Sept. 11. 0-0. 124. CBS. 0-0. 32. KC -6. 4:25 p.m. ET

The Cardinals have been a soap opera all offseason. Meanwhile, Patrick Mahomes has heard nothing but bizarre criticism from former teammates and media alike. Not a good combination for Arizona.

Pick: Kansas City 35, Arizona 24

13. 28. Sunday, Sept. 11. 0-0. LAC -3.5. 4:25 p.m. ET. 0-0. CBS

Two high-powered attacks going at it in Los Angeles. The Chargers are the superior squad, but if their pass rush doesn’t get home, Derek Carr could have an enormous day. The problem for Las Vegas? It probably does.

Pick: Los Angeles 30, Las Vegas 27

0-0. 48. Sunday, Sept. 11. TB -2.5. NBC. 0-0. 123. 8:20 p.m. ET

Sunday Night Football kicks off with a great game. Dallas is trying to erase last year’s ugly playoff loss from memory, while the Buccaneers are in a war with Father Time. Tampa Bay has endured ample injuries already, but can the Cowboys take advantage?

Pick: Tampa Bay 29, Dallas 27

Monday, Sept. 12. DEN -6.5. 45. ESPN. 0-0. 36. 8:15 p.m. ET. 0-0

This feels like a game with a ton of build-up that’s over by halftime. Denver is a good team with a great quarterback in Russell Wilson. The Seahawks, motivated as they might be, have Geno Smith under center. Not good.

Pick: Denver 31, Seattle 12

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