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DraftKings NFL 2022: Best daily fantasy lineup for Week 10

By Frankie Licausi

Nov 6, 2022; Chicago, Illinois, USA; Chicago Bears quarterback Justin Fields (1) rushes the ball for a touchdown against the Miami Dolphins during the second half at Soldier Field. Mandatory Credit: Mike Dinovo-USA TODAY Sports
Nov 6, 2022; Chicago, Illinois, USA; Chicago Bears quarterback Justin Fields (1) rushes the ball for a touchdown against the Miami Dolphins during the second half at Soldier Field. Mandatory Credit: Mike Dinovo-USA TODAY Sports /
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Oct 30, 2022; Seattle, Washington, USA; New York Giants running back Saquon Barkley (26) returns to the bench after rushing for a touchdown against the Seattle Seahawks during the second quarter at Lumen Field. Mandatory Credit: Joe Nicholson-USA TODAY Sports
Oct 30, 2022; Seattle, Washington, USA; New York Giants running back Saquon Barkley (26) returns to the bench after rushing for a touchdown against the Seattle Seahawks during the second quarter at Lumen Field. Mandatory Credit: Joe Nicholson-USA TODAY Sports /

RB1: Saquon Barkley, New York Giants ($8,600)

Saquon Barkley is the top-ranked running back this week. The top fantasy running back going up against the worst rushing defense is usually a recipe for success. Barkley has been a league-winning steal in fantasy football, as he fell to at least the second round in most drafts. His usage combined with his elite skillset make for obvious production.

Barkley’s high price this week will be worth it, as he has the upside of a Joe-Mixon-Week-Nine-esque performance this week. The Texans allow the most fantasy points per game against running backs this year and haven’t been able to stop anybody. Barkley won’t be an exception in Week 10.

RB2: Jamaal Williams, Detroit Lions ($5,900)

Jamaal Williams has been a low-key RB2 in fantasy football this season. In fact, he’s currently ranked as the overall RB15 on the year in PPR leagues. With the Lions continuing to hold D’Andre Swift back because of health issues, or whatever else it may be, Williams has continued to be a borderline workhorse for Detroit.

Williams takes on the Chicago Bears this week, who either win by running the ball or lose by allowing their teammates to run the ball. They have the third-worst run defense in the NFL and allow the fifth-most fantasy points per game to the position. Williams is a sneaky top-15 play this week.

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