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NFL Week 10 2020: Picks and predictions for every game

By Matt Verderame

ORCHARD PARK, NEW YORK - NOVEMBER 08: Josh Allen #17 of the Buffalo Bills celebrates a touchdown during the second half against the Seattle Seahawks at Bills Stadium on November 08, 2020 in Orchard Park, New York. (Photo by Timothy T Ludwig/Getty Images)
ORCHARD PARK, NEW YORK - NOVEMBER 08: Josh Allen #17 of the Buffalo Bills celebrates a touchdown during the second half against the Seattle Seahawks at Bills Stadium on November 08, 2020 in Orchard Park, New York. (Photo by Timothy T Ludwig/Getty Images) /
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Derrick Henry, Tennessee Titans
NASHVILLE, TENNESSEE – OCTOBER 18: Running back Derrick Henry #22 of the Tennessee Titans runs with the ball in the third quarter against the Houston Texans at Nissan Stadium on October 18, 2020 in Nashville, Tennessee. The Titans defeated the Texans 42-36 in overtime. (Photo by Frederick Breedon/Getty Images) /

Week 10 of the 2020 NFL season is full of important divisional tilts, including two in primetime and another on Sunday afternoon.

As always, all odds courtesy of OddsShark.

5-3. 46. FOX. Thursday, Nov. 12. 35. TEN -1. 8:20 p.m. ET. 6-2

Great Thursday night game. The winner controls the AFC South, and if it’s Tennessee, the Titans have a two-game lead heading towards Thanksgiving. We’ll know plenty about the division over the next three weeks, with the rematch coming Nov. 29.

Pick: Tennessee 27, Indianapolis 24

CBS. 1 p.m. ET. 10. Sunday, Nov. 15. 5-3. 53. CLE -3. 2-6

If the Browns can’t win this game, at home, off a bye, they don’t deserve to make the playoffs. At 5-3, this is a must-win for Cleveland, which lost to the Raiders before getting the week off. Baker Mayfield needs to come up big.

Pick: Cleveland 31, Houston 26

52. Sunday, Nov. 15. 49. 1 p.m. ET. 1-7. CBS. 6-2. GB -14

The bloodbath of the week. Tough to see Jake Luton going into Lambeau Field and keeping this game remotely competitive. Green Bay knows its can start putting away the NFC North with the Bears sputtering, and it won’t miss this opportunity.

Pick: Green Bay 42, Jacksonville 17

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