USC vs. San Jose State prediction, odds, spread, line, over/under & betting info for NCAA Week 1

USC Trojans quarterback Kedon Slovis. (Robert Hanashiro-USA TODAY Sports)
USC Trojans quarterback Kedon Slovis. (Robert Hanashiro-USA TODAY Sports) /

The USC Trojans start the 2021 season at home against the San Jose State Spartans. Here’s all you need to know going into Week 1.

USC fell just short of the Pac-12 title last season. The San Jose State Spartans grabbed hold of the Mountain West Championship.

The differing fates of the two teams in 2020 don’t matter now. All that counts is the team on top of the scoreboard when they face off on Saturday at the Los Angeles Memorial Coliseum.

Clay Helton and his team know the pressure they face to take the next step. Brent Brennan and the Spartans should have a chip on their shoulder trying to prove they can repeat after being picked third in the Mountain West preseason poll.

Will the Trojans start their season on the right foot? Or will the Spartans play spoiler?

USC vs. San Jose State odds for Week 1

The opening line had the Trojans favored by 16.5 points over the Spartans, it’s remained in that range with an over/under of 56.5 points.

USC injury report vs. San Jose State in Week 1

USC will be without a slew of fringe players including linebacker Jordan Iosefa, linebacker Tayler Katoa, defensive back Briton Allen, cornerback Adonis Otey, quarterback Mo Hasan and wide receiver Jake Smith.

Questions surround the status of tight end Malcolm Epps with turf toe. However, running back Keontay Ingram, wide receiver Gary Bryant Jr. and defensive end Korey Foreman should be available despite slight injuries.

Bru McCoy suspension update

Highly-touted wide receiver Bru McCoy was suspended earlier this summer over a domestic violence arrest. Prosecutors dropped the charges, but he is still going through the university’s Title IX office review process. His suspension is still in place.

USC vs. San Jose State prediction for Week 1

Helton-coached teams aren’t known for their quick starts. Past matchups against Group of Five opposition have ended in ugly victories. So why expect something different this year?

The Trojans will have too much talent to go down, but the Spartans will make it tougher on them than expected. Look for Kedon Slovis to turn up the heat in the fourth quarter to get USC out of early trouble.

Prediction: USC 30-San Jose State 21

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USC next game & schedule

The Trojans will open the Pac-12 slate with their familiar early-season matchup against Stanford at the Coliseum on Sept. 11.

What channel is the USC game on in Week 1

Do you have Pac-12 Network in your television subscription? Congratulations! You can watch the USC vs. San Jose State broadcast starting live at 5:00 p.m. ET / 2:00 p.m. PT.

USC vs. San Jose State live stream

If you won’t be in front of a TV or need a live stream of the game because Pac-12 Network isn’t part of your subscription, fear not. It’s easy to find on FuboTV instead.

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