College football Week 4 schedule and predictions for every Top 25 game

Sep 18, 2021; College Station, Texas, USA; Texas A&M Aggies quarterback Zach Calzada (10) and wide receiver Demond Demas (1) and wide receiver Yulkeith Brown (8) celebrate after the game between the Texas A&M Aggies and the New Mexico Lobos at Kyle Field. Mandatory Credit: Jerome Miron-USA TODAY Sports
Sep 18, 2021; College Station, Texas, USA; Texas A&M Aggies quarterback Zach Calzada (10) and wide receiver Demond Demas (1) and wide receiver Yulkeith Brown (8) celebrate after the game between the Texas A&M Aggies and the New Mexico Lobos at Kyle Field. Mandatory Credit: Jerome Miron-USA TODAY Sports /
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College football schedule for Week 4 and predictions for all the biggest games, including Texas A&M at Arkansas and Notre Dame at Wisconsin.

It seems like the 2021 season has already had more than its share of surprises. Here we are headed into week Week 4, and it’s the fourth straight week with at least two ranked-versus-ranked games. We have already seen plenty of upsets, near misses, and three would-be high-powered offenses, and one potential first-overall pick, sputter.

Last week’s picks were a train wreck. There are no two ways about it. From West Virginia beating Virginia Tech through Fresno State knocking off UCLA, it was a start to finish disaster.  But as Ted Lasso taught us, we are goldfish. Last week is last week. This week’s games need picking!

College football Week 4 schedule and predictions

Predicted winner in bold

Friday, September 24 (10:00 p.m. ET)

UNLV at No. 22 Fresno State

Saturday, September 25 (12:00 p.m. ET)

No. 2 Georgia at Vanderbilt

Villanova at No. 6 Penn  State

No. 12 Notre Dame at No. 18 Wisconsin

Saturday, September 25 (1:00 p.m. ET)

UMass at No. 17 Coastal Carolina

Saturday, September 25 (3:30 p.m. ET)

Colorado State at No. 5 Iowa

No. 7 Texas A&M at No. 16 Arkansas

No. 9 Clemson at NC State

No. 14 Iowa State at Baylor

Rutgers at No. 19 Michigan

Saturday, September 25 (4:00 p.m. ET)

Georgia State at No. 23 Auburn

Saturday, September 25 (6:00 p.m. ET)

No. 24 UCLA at Stanford

Saturday, September 25 (7:00 p.m. ET)

Tennessee at No. 11 Florida

Nebraska at No. 20 Michigan State

No. 25 Kansas State at Oklahoma State

Saturday, September 25 (7:30 p.m. ET)

Southern Miss at No. 1 Alabama

West Virginia at No. 4 Oklahoma

Akron at No. 10 Ohio State

No. 21 North Carolina at Georgia Tech

Saturday, September 25 (10:15 p.m. ET)

South Florida at No. 15 BYU

Saturday, September 25 (10:30 p.m. ET)

Arizona at No. 3 Oregon

TV listings for the college football Week 4 schedule can be found here. Every college football game this week can be streamed via fuboTV.

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