5 best fantasy football matchups to exploit for Week 6

Oct 10, 2021; Pittsburgh, Pennsylvania, USA; Pittsburgh Steelers wide receiver Diontae Johnson (18) catches a fifty yard touchdown pass behind Denver Broncos cornerback Kyle Fuller (23) during the first quarter at Heinz Field. Mandatory Credit: Charles LeClaire-USA TODAY Sports /

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Oct 10, 2021; Pittsburgh, Pennsylvania, USA; Pittsburgh Steelers running back Najee Harris (22) runs the ball against the Denver Broncos during the second quarter at Heinz Field. Mandatory Credit: Charles LeClaire-USA TODAY Sports /

1. RB Najee Harris vs. the Seattle Seahawks

We’re double-dipping this week against a league-worst Seattle defense, but for good reason. This time it’s Najee Harris, who has seen massive volume with 106 total touches through five games. That’s impressive for any back, let alone a rookie.

Harris is in a smash spot this week, and could be in for even more passing work with the loss of Smith-Schuster. Any more volume for Harris would likely have him ascend to surefire top-five running back territory, if he isn’t already there.

If the Steelers treacherous offensive lineman can hold off the Seahawks’ interior defensive lineman, things will bode even better for Harris this week.

The Seahawks are allowing 145.2 rushing yards a game, so you can bet on Harris reaching the century mark this week as a guaranteed top-ten back in fantasy in both regular season leagues and daily leagues. He’s in prime position to win players their matchups this week with a huge outing.

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