The Broncos are coming off the bye and desperately need to win. The Chargers can get back into first place of the AFC West with a win, while Denver would force its way back into the conversation.
Pick: Los Angeles 30, Denver 25
Rough matchup for the Packers. Green Bay has a hurting quarterback, a bevy of injured offensive lineman and potentially no Aaron Jones in the backfield. All that, and facing a well-rested Rams team with a front that includes Aaron Donald and Von Miller.
Pick: Los Angeles 26, Green Bay 20
Critical game in the NFC playoff picture. The winner gains a game on the other and, as importantly, gets a tiebreaker.
Pick: San Francisco 30, Minnesota 27
Why should anybody believe Baker Mayfield is winning this game? Credit to him for playing through injuries, but he looks pedestrian, to be kind.
Pick: Baltimore 24, Cleveland 20
Washington can get into the postseason scrum by winning, while the Seahawks look adrift in a sea of defeats.
Pick: Washington 29, Seattle 24
Last Week: 11-4
Season: 100-64