2022 NFL Schedule Release: Picks and predictions for every game

KANSAS CITY, MISSOURI - JANUARY 23: Josh Allen #17 of the Buffalo Bills takes the field prior to the AFC Divisional Playoff game against the Kansas City Chiefs at Arrowhead Stadium on January 23, 2022 in Kansas City, Missouri. (Photo by David Eulitt/Getty Images)
KANSAS CITY, MISSOURI - JANUARY 23: Josh Allen #17 of the Buffalo Bills takes the field prior to the AFC Divisional Playoff game against the Kansas City Chiefs at Arrowhead Stadium on January 23, 2022 in Kansas City, Missouri. (Photo by David Eulitt/Getty Images) /
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Sean McVay, Aaron Donald, Rams
Rams head coach Sean McVay with Aaron Donald and Matthew Stafford. (Mark J. Rebilas-USA TODAY Sports) /

We’ve done it. It’s the 2022 NFL Schedule Release, and below are the picks and predictions for all 285 games right through Super Bowl LVII.

A new season is upon us.

Free agency is over. The 2022 NFL Draft is finished. The preseason? Done.

We know the rosters for the 32 teams, and we know their path to Super Bowl LVII.

This year is unique in a variety of ways. We’ve seemingly moved past the COVID era. Additionally, the offseason brought an unparalleled amount of change at the quarterback position, with Matt Ryan, Deshaun Watson, Russell Wilson, Carson Wentz and others moving around.

Now, it’s my time-honored here at FanSided to pick every regular-season game and then roll through the Super Bowl, predicting who will hoist the Lombardi Trophy come February.

Picks for all 272 NFL regular-season games through Super Bowl LVII

Week 1

Thursday Night Football

. 28. 16. 24. 51. . .

Sunday afternoon

. 30. . . 25. 26. . 18

57. . 20. 42. . . 13.

. 14. . 19. 44. . 15.

24. . 27. 54. . 50. .

10. . . 26. . . 17. 46

58. . 30. 52. . 20. .

. 21. 59. . 47. . . 23

35. . . . 20. 31. 35.

23. 60. . 49. . 32. .

41. 56. . . 24. . . 55

19. . . . 53. . 23. 87

. 24. 32. . . . 34. 124

28. 28. 38. 13. . . .

Sunday Night Football

. 34. 123. . . . 31. 48

Monday Night Football

. 45. . . 21. 36. . 38

Game of the Week: Buffalo Bills at Los Angeles Rams

Preview of Super Bowl LVII on opening night? Quite possible.

Buffalo hasn’t reached Super Sunday since 1993, but the Bills are favorites to win the Lombardi Trophy for the first time in their hoister. Of course, the Rams know the feeling, having hoisted it in their own building last February after beating the Cincinnati Bengals.

For the Bills, it’s a nice litmus test to see where they are at this point in the campaign. Buffalo is loaded up on both sides of the ball, including Von Miller, who will return to Los Angeles and see some old friends. Miller signed a six-year deal worth $120 million in the offseason, stunning most around the league with his departure. The Rams didn’t replace him, hoping their remaining stars can pick up his proverbial slack.

As for Los Angeles, this might be the toughest home game on what is a brutal docket, including tilts with the San Francisco 49ers, Arizona Cardinals, Denver Broncos, Las Vegas Raiders and Dallas Cowboys. With a victory here, the Rams would strengthen their position in the tough NFC West, albeit with a non-conference win.

Finally, if you love strong-armed quarterbacks, watching Matthew Stafford and Josh Allen indoors is the game for you.