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5 best fantasy football matchups to exploit for Week 1

By Frankie Licausi

Aug 20, 2022; Jacksonville, Florida, USA; Jacksonville Jaguars quarterback Trevor Lawrence (16) drops back to pass against the Pittsburgh Stealers in the second quarter at TIAA Bank Field. Mandatory Credit: Nathan Ray Seebeck-USA TODAY Sports
Aug 20, 2022; Jacksonville, Florida, USA; Jacksonville Jaguars quarterback Trevor Lawrence (16) drops back to pass against the Pittsburgh Stealers in the second quarter at TIAA Bank Field. Mandatory Credit: Nathan Ray Seebeck-USA TODAY Sports /
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Dec 26, 2021; Philadelphia, Pennsylvania, USA; Philadelphia Eagles running back Miles Sanders (26) reacts as he takes the field before a game against the New York Giants at Lincoln Financial Field. Mandatory Credit: Bill Streicher-USA TODAY Sports
Dec 26, 2021; Philadelphia, Pennsylvania, USA; Philadelphia Eagles running back Miles Sanders (26) reacts as he takes the field before a game against the New York Giants at Lincoln Financial Field. Mandatory Credit: Bill Streicher-USA TODAY Sports /

3. Miles Sanders vs. Detroit Lions

Miles Sanders has been an often-debated name amongst fantasy circles this offseason. On one hand, he only had five games last season with 15 or more touches, which is low for someone who you’re counting on for starting-caliber production. On the other hand, he’s the RB1 for the Eagles’ up-and-coming offense with little touch competition behind him.

Season-long, we can debate Sanders’ draft value, but for Week 1 against Detroit, he’s guaranteed to have at least a decent fantasy day. The 28th-ranked run defense last year, the Lions will likely have another tough year watching running backs carve them up this season. The first test will be Sanders.

Sanders is an RB2/flex play this week, with higher upside due to this matchup. In terms of daily fantasy, there are worse options than Sanders in the mid-tiers of running backs.

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