NFL Week 6 schedule: Cardinals, Rams among teams on upset alert

LANDOVER, MD - OCTOBER 11: Robert Woods #17 of the Los Angeles Rams runs with the ball after a catch in the first quarter against Kendall Fuller #29 of the Washington Football Team at FedExField on October 11, 2020 in Landover, Maryland. (Photo by Greg Fiume/Getty Images)
LANDOVER, MD - OCTOBER 11: Robert Woods #17 of the Los Angeles Rams runs with the ball after a catch in the first quarter against Kendall Fuller #29 of the Washington Football Team at FedExField on October 11, 2020 in Landover, Maryland. (Photo by Greg Fiume/Getty Images) /
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MINNEAPOLIS, MN – SEPTEMBER 27: Ryan Tannehill #17 of the Tennessee Titans jogs to the sidelines during a timeout in the second quarter of the game against the Minnesota Vikings at U.S. Bank Stadium on September 27, 2020, in Minneapolis, Minnesota. (Photo by Stephen Maturen/Getty Images)
MINNEAPOLIS, MN – SEPTEMBER 27: Ryan Tannehill #17 of the Tennessee Titans jogs to the sidelines during a timeout in the second quarter of the game against the Minnesota Vikings at U.S. Bank Stadium on September 27, 2020, in Minneapolis, Minnesota. (Photo by Stephen Maturen/Getty Images) /

The Cardinals and Rams should be on upset alert in Week 6.

Navigating the regular season will be a challenge for NFL teams filled with athletes that are creatures of habit. The schedule has become a moving target thanks to COVID issues while the amount of devastating injuries has drastically changed the outlook of offenses.

That uncertainty can certainly lead to upsets like we called last week with the Indianapolis Colts, who fell on the road to Cleveland despite being 2.5 point favorites. Let’s take a look at three more teams that need to be on upset alert as we hit Week 6 of the season. Odds are courtesy of the FanDuel Sportsbook.

The Titans need to be on upset alert against Houston

This week will be a strange one for Tennessee, which will play two games in five days after having an early bye due to their COVID outbreak. All of the Titans’ attention was on Tuesday’s game against Buffalo but they will have a tough turnaround against a talented Houston Texans’ team on Sunday.

Houston finally made it into the win column with a 30-16 victory over the Jacksonville Jaguars on Sunday as they looked like a much sharper team after Bill O’Brien was fired. Deshaun Watson played his most effective football of the season as well, going 25 of 35 for 359 yards with three touchdowns in the win.

This game will come on short rest for Tennessee, which will only have a few days to prepare for a divisional rival that beat them on their home field last year. Don’t be shocked if the Titans play a very close game and lose in the end on a late drive by Watson.