San Francisco 49ers Odds

Latest San Francisco 49ers Betting Odds, Point Spread, Totals, Props, Parlay Picks, Predictions and Moneyline.

Miami Dolphins quarterback Tua Tagovailoa (1)

Dolphins vs. 49ers Prediction and Odds for NFL Week 13 (Back Miami's Offense to Rally vs. San Francisco's Defense)

NFL Week 13 Schedule, Odds, Lines and Over/Unders (Every Team's Spread, Moneyline and Total

5 Stats to Know When Placing Your NFL Week 12 Bets

Saints vs. 49ers Prediction and Odds for NFL Week 12 (New Orleans is Better Than Record Indicates)

Oct 9, 2022; Glendale, Arizona, USA; Arizona Cardinals running back James Conner (6) runs for a big gain.

Monday Night Football Best Bets for 49ers vs. Cardinals (Back Arizona to Make Monday in Mexico City More Fun)

San Francisco 49ers tight end George Kittle celebrates a touchdown in their victory over the L.A. Rams back in October.

Monday Night Football Best Same Game Parlay Picks for 49ers vs. Cardinals (Go Back to George Kittle in Mexico City)

Arizona Cardinals head coach Kliff Kingsbury talks to backup QB Colt McCoy in their Week 10 matchup.

Kliff Kingsbury, Cardinals are Perfect Underdog Play vs. 49ers on Monday Night Football

Arizona Cardinals running back James Conner.

Monday Night Football Best Anytime TD Scorer Picks for 49ers vs. Cardinals

San Francisco 49ers wide receiver Brandon Aiyuk.

Monday Night Football Best Prop Bets for 49ers vs. Cardinals (Trust DeAndre Hopkins, Brandon Aiyuk)

Due to several feet of snow, Highmark Stadium in Buffalo, N.Y. the Cleveland Browns vs. Buffalo Bills game was moved to Ford Field in Detroit.

NFL Weather Report for Week 11 (What's the Forecast for Every NFL Team and Matchup Today?)

Minnesota Vikings quarterback Kirk Cousins is 7-14 straight up in late afternoon games over his career. They host the Dallas Cowboys at 4:25 p.m. ET.

NFL Week 11 Betting Trends and Odds for Every Team, Every Game

Dallas Cowboys quarterback Dak Prescott and running back Tony Pollard should be a major part of the game plan vs. the Minnesota Vikings in Week 11.

NFL Week 11 Games to Bet Before the Lines Move (Don't Overreact to Cowboys Loss, Vikings Win in Week 10)

Arizona Cardinals head coach Kliff Kingsbury has been most successful in his NFL career as an underdog, going 22-11-2 ATS.

49ers vs. Cardinals Prediction and Odds for NFL Week 11 (Multiple Trends Back Arizona as Big Home Dog)

Nov 6, 2022; Atlanta, Georgia, USA; Los Angeles Chargers quarterback Justin Herbert (10) throws a

Chargers vs. 49ers Best Same Game Parlay Picks for Sunday Night Football

Oct 9, 2022; Charlotte, North Carolina, USA; San Francisco 49ers fullback Kyle Juszczyk (44) with

Chargers vs. 49ers Best Anytime Touchdown Scorer Picks for Sunday Night Football

Oct 2, 2022; Houston, Texas, USA; Los Angeles Chargers tight end Gerald Everett (7) celebrates with

Chargers vs. 49ers Best Prop Bets for Sunday Night Football (Gerald Everett Underrated Weapon for Los Angeles)

Oct 23, 2022; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey

49ers Will Run All Over Chargers' League Worst Run Defense

San Francisco 49ers running back Christian McCaffrey could be in for a massive day against an L.A. Chargers run defense that ranks worst in the NFL.

NFL Week 10 Betting Trends for Every Team, Every Game

Miami Dolphins quarterback Tua Tagovailoa (1) is seen in the team tunnel prior to the start of the

3 NFL Futures Bets to Make Halfway Through the Season

Nov 6, 2022; Atlanta, Georgia, USA; Los Angeles Chargers quarterback Justin Herbert (10) passes

3 Super Bowl Long Shot Bets to Make Halfway Through the NFL Season

San Francisco 49ers running back Christian McCaffrey (23)

Chargers vs. 49ers Prediction and Odds for NFL Week 10 (Brandon Staley Better Learn How to Stop the Run)

Los Angeles Rams running back Cam Akers (3).

Is Cam Akers Playing Today? (Latest Update for 49ers vs. Rams in NFL Week 8)

San Francisco 49ers running back Christian McCaffrey

Best NFL Props for 49ers vs. Rams in NFL Week 8 (Shanahan is Ready to Unleash CMC)

San Francisco 49ers running back Christian McCaffrey

49ers vs. Rams Prediction: Shanahan Continues to Own McVay in this NFC West Rivalary

San Francisco 49ers running back Christian McCaffrey played his first snap in a new uniform in Week 7 vs. the Kansas City Chiefs.

When is the 2022 NFL Trade Deadline? (Times, Dates, Trade Rumors and Latest Odds)

Oct 23, 2022; Santa Clara, California, USA; Kansas City Chiefs running back Clyde Edwards-Helaire

Net Yards Per Play Report: Chiefs Rise in Rankings After Dominant Win Over 49ers

San Francisco 49ers running back Christian McCaffrey is expected to have a full workload when the 49ers face the L.A. Rams in Los Angeles in Week 8.

49ers vs. Rams Prediction, Odds, Spread and Over/Under for NFL Week 8

Las Vegas Raiders running back Josh Jacobs (28) celebrates his touchdown during a win at home.

Best NFL Prop Bets Today (Josh Jacobs Runs Wild and Free vs. Texans at Home)